An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse model. - Wikidata - awgldk - TriplyDB

An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse model.

An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse model.

http://www.wikidata.org/entity/Q36171933

about

Regulation of the latent-lytic switch in Epstein-Barr virus PD-1/CTLA-4 Blockade Inhibits Epstein-Barr Virus-Induced Lymphoma Growth in a Cord Blood Humanized-Mouse Model Epstein-Barr virus lytic reactivation regulation and its pathogenic role in carcinogenesis Rectal transmission of transmitted/founder HIV-1 is efficiently prevented by topical 1% tenofovir in BLT humanized mice Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic Signaling Herpesviruses dUTPases: A New Family of Pathogen-Associated Molecular Pattern (PAMP) Proteins with Implications for Human Disease Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter.PARP1 restricts Epstein Barr Virus lytic reactivation by binding the BZLF1 promoter Humanized mouse models of epstein-barr virus infection and associated diseases.Differences in gastric carcinoma microenvironment stratify according to EBV infection intensity: implications for possible immune adjuvant therapy.Modeling EBV infection and pathogenesis in new-generation humanized mice.LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesis.Epstein-Barr virus transcription factor Zta acts through distal regulatory elements to directly control cellular gene expression.Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial Cells Knockout of Epstein-Barr virus BPLF1 retards B-cell transformation and lymphoma formation in humanized mice.Effects of lymphocyte profile on development of EBV-induced lymphoma subtypes in humanized mice.Prognostic value of TROP2 in human nasopharyngeal carcinoma.The cellular ataxia telangiectasia-mutated kinase promotes epstein-barr virus lytic reactivation in response to multiple different types of lytic reactivation-inducing stimuli 5-hydroxymethylation of the EBV genome regulates the latent to lytic switch.EBV reactivation as a target of luteolin to repress NPC tumorigenesis.Cell-based screening assay for antiviral compounds targeting the ability of herpesvirus posttranscriptional regulatory proteins to stabilize viral mRNAs.Epstein-Barr virus and human herpesvirus 6 detection in a non-Hodgkin's diffuse large B-cell lymphoma cohort by using RNA sequencing.Reproduction of epstein-barr virus infection and pathogenesis in humanized mice.Potential of protein kinase inhibitors for treating herpesvirus-associated disease.Dynamic Epstein-Barr virus gene expression on the path to B-cell transformation.Modes of infection and oncogenesis by the Epstein-Barr virus.Regulation of Epstein-Barr virus reactivation from latency.Role of epigenetics in EBV regulation and pathogenesis.Epstein-Barr virus infection and persistence in nasopharyngeal epithelial cells.The role of Epstein-Barr virus in epithelial malignancies.Epigenetic Alterations in Epstein-Barr Virus-Associated Diseases.Human papillomavirus promotes Epstein-Barr virus maintenance and lytic reactivation in immortalized oral keratinocytes.Murine Models of Epstein-Barr Virus-Associated Lymphomagenesis.Epstein-Barr virus: more than 50 years old and still providing surprises.Modeling Natural Killer Cell Targeted Immunotherapies.Shutoff of BZLF1 gene expression is necessary for immortalization of primary B cells by Epstein-Barr virus.Epstein-Barr virus infection and nasopharyngeal carcinoma.Lytic EBV infection investigated by detection of Soluble Epstein-Barr virus ZEBRA in the serum of patients with PTLD.Latent Membrane Protein 1 (LMP1) and LMP2A Collaborate To Promote Epstein-Barr Virus-Induced B Cell Lymphomas in a Cord Blood-Humanized Mouse Model but Are Not Essential.Age and cellular composition influence overall survival in a collective of non-immunocompromised patients with EBV-positive diffuse large B-cell lymphoma from a German lymphoma center.

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An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse model.

http://www.wikidata.org/entity/Q36171933

description

2012 nî lūn-bûn

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name

An Epstein-Barr Virus (EBV) mu ...... on in a humanized mouse model.

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P1433

Journal of Virology

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An Epstein-Barr Virus (EBV) mu ...... on in a humanized mouse model.

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P2093

Erik Reinheim

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Janet E Mertz

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Jenny E Gumperz

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Margaret L Gulley

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Shannon C Kenney

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Shi-Dong Ma

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Weihua Tang

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William J Burlingham

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Xianming Yu

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Ying Zhou

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P2860

Epstein-barr virus immediate-early protein BZLF1 is SUMO-1 modified and disrupts promyelocytic leukemia bodies

Priming of protective T cell responses against virus-induced tumors in mice with human immune system components

ZEB1 regulates the latent-lytic switch in infection by Epstein-Barr virus

The B-cell specific transcription factor, Oct-2, promotes Epstein-Barr virus latency by inhibiting the viral immediate-early protein, BZLF1

Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex

The dynamics of EBV shedding implicate a central role for epithelial cells in amplifying viral output

Immediate early and early lytic cycle proteins are frequent targets of the Epstein-Barr virus-induced cytotoxic T cell response

A phase 1/2 trial of arginine butyrate and ganciclovir in patients with Epstein-Barr virus-associated lymphoid malignancies.

CD34+ cord blood cell-transplanted Rag2-/- gamma(c)-/- mice as a model for Epstein-Barr virus infection

Methylation-dependent binding of the epstein-barr virus BZLF1 protein to viral promoters

P304

7976-7987

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scholarly article

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10.1128/JVI.00770-12

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15

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86

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2012-05-23T00:00:00Z

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22623780

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Epstein–Barr virus

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3421695

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