The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development. - Wikidata - awgldk - TriplyDB

The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development.

The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development.

http://www.wikidata.org/entity/Q36193517

about

The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability Notch signaling: its roles and therapeutic potential in hematological malignancies Targeting Notch to overcome radiation resistance From fly wings to targeted cancer therapies: a centennial for notch signaling Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond Murine Models of Splenic Marginal Zone Lymphoma: A Role for Cav1?Antiviral therapy of hepatitis C as curative treatment of indolent B-cell lymphoma The Link between Autoimmunity and Lymphoma: Does NOTCH Signaling Play a Contributing Role?The role of aberrant proteolysis in lymphomagenesis Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma Identification of a human splenic marginal zone B cell precursor with NOTCH2-dependent differentiation properties.Diffuse large B-cell lymphoma: can genomics improve treatment options for a curable cancer?Genetics of follicular lymphoma transformation.IκB kinase β (IKBKB) mutations in lymphomas that constitutively activate canonical nuclear factor κB (NFκB) signaling.Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients.BRAF kinase domain mutations are present in a subset of chronic myelomonocytic leukemia with wild-type RAS.Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia Hajdu-Cheney syndrome: a review.NOTCH1 mutations influence survival in chronic lymphocytic leukemia patients.Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry.The truncate mutation of Notch2 enhances cell proliferation through activating the NF-κB signal pathway in the diffuse large B-cell lymphomas.A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features.Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing.Whole exome sequencing of microdissected splenic marginal zone lymphoma: a study to discover novel tumor-specific mutations.Extreme Outlier Analysis Identifies Occult Mitogen-Activated Protein Kinase Pathway Mutations in Patients With Low-Grade Serous Ovarian Cancer.Hajdu Cheney Mouse Mutants Exhibit Osteopenia, Increased Osteoclastogenesis, and Bone Resorption.The NOTCH pathway is recurrently mutated in diffuse large B-cell lymphoma associated with hepatitis C virus infection.Toll-like receptor stimulation in splenic marginal zone lymphoma can modulate cell signaling, activation and proliferation.Molecular etiology of an indolent lymphoproliferative disorder determined by whole-genome sequencing A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes.Notch Signaling and the Skeleton.The genetics of nodal marginal zone lymphoma Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome Landscape of somatic mutations and clonal evolution in mantle cell lymphoma.Germline and somatic genetic variations of TNFAIP3 in lymphoma complicating primary Sjogren's syndrome.IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity.High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias.The genetic landscape of dural marginal zone lymphomas.

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P2860

The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development.

http://www.wikidata.org/entity/Q36193517

description

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2012年论文

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The coding genome of splenic m ...... ing marginal zone development.

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The coding genome of splenic m ...... ing marginal zone development.

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Journal of Experimental Medicine

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The coding genome of splenic m ...... ing marginal zone development.

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Alessio Bruscaggin

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Andrea Rinaldi

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Antony Holmes

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Carmela Ciardullo

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Clara Deambrogi

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Claudio Agostinelli

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Daniela Piranda

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Davide Rossi

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Fabio Facchetti

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Fabrizio Tabbò

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P2860

Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss

TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

ARID1A mutations in endometriosis-associated ovarian carcinomas

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.

Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia.

Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma.

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1537-1551

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10.1084/JEM.20120904

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9

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209

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Laura Pasqualucci

Gianluca Gaidano

Francesca Arruga

Giorgio Inghirami

Fabrizio Tabbò

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2012-08-13T00:00:00Z

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230666744

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22891273

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3428941

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