Progression toward tumor cell phenotype is enhanced by overexpression of a mutant p53 tumor-suppressor gene isolated from nasopharyngeal carcinoma.
about
Clinical and pathologic relevance of p53 index in canine osseous tumorsMitochondrial uncoupling inhibits p53 mitochondrial translocation in TPA-challenged skin epidermal JB6 cellsA functional investigation of tumor suppressor gene activities in a nasopharyngeal carcinoma cell line HONE1 using a monochromosome transfer approach.The significance of immunohistochemistry in the diagnosis and therapy of neoplasms.Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.Germ-line mutations in the von Hippel-Lindau tumor-suppressor gene are similar to somatic von Hippel-Lindau aberrations in sporadic renal cell carcinoma.Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma.Mechanisms and markers of carcinogenesis and neoplastic progression.Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation.Specific interaction of mutant p53 with regions of matrix attachment region DNA elements (MARs) with a high potential for base-unpairing.Mutant p53 in cancer: new functions and therapeutic opportunities.Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras.Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete C-terminal domain.Ectopic expression of cdc2/cdc28 kinase subunit Homo sapiens 1 uncouples cyclin B metabolism from the mitotic spindle cell cycle checkpoint.Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP.An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations.Transcriptional activation of the human glutathione peroxidase promoter by p53.Mitogen-activated protein kinase is involved in the degradation of p53 protein in the bryostatin-1-induced differentiation of the acute promyelocytic leukemia NB4 cell line.Molecular cloning of mouse tissue inhibitor of metalloproteinases-3 and its promoter. Specific lack of expression in neoplastic JB6 cells may reflect altered gene methylation.Functional characterization of p53 molecules expressed in human squamous cell carcinomas of the head and neck.Relationship between radiation response and p53 status in human bladder cancer cells.Inhibition of the putative tumor suppressor gene TIMP-3 by tumor-derived p53 mutants and wild type p53.Correlation of p21 gene codon 31 polymorphism and TNF-alpha gene polymorphism with nasopharyngeal carcinoma.Live-Cell Mesothelioma Biobank to Explore Mechanisms of Tumor Progression.p53 represses CAAT enhancer-binding protein (C/EBP)-dependent transcription of the albumin gene. A molecular mechanism involved in viral liver infection with implications for hepatocarcinogenesis.
P2860
Q28201920-936D4808-D89A-4516-BD8A-E11D757F2E77Q28475829-CE3128C2-8BFD-41AA-9547-BFFB65E6D611Q34507847-5848F3C2-F21A-4538-BDD9-DD957A42DC17Q34602545-436B4AA6-38E2-46AA-99F1-3E907D7FA987Q34987802-1E9D78CA-0A66-4D89-8702-DCDE364A953EQ35889809-260BAAB6-EB37-41AA-8009-CF4715C678AFQ36078222-0E3E21CD-B157-4233-9036-958D7E8437C9Q36273391-692F3168-D4DF-4412-9656-74BCA0DD06D5Q36706938-A75EF2E9-EA2D-4068-99BE-4091075359A4Q36796242-4BD96661-4826-454C-A8D1-76C3AAFD5E5BQ38197826-9E4BD0D2-6230-48A5-9ACC-4846B7673FE6Q39467174-0A3D9AB0-60C2-469C-A379-F61CA1BE23E6Q39575066-50FAB596-BA03-41D9-B4C7-86297634EE62Q39576374-F7B65400-CDE6-4EDB-A25C-E0A720EAFD41Q39602480-82D99408-DE66-4271-B2E1-17AB22BB480EQ40198133-81575376-3F5D-4C93-96F9-132B3FC42B7AQ40960162-47C2B129-120B-4045-96F6-4283A0A0BAAAQ40982606-DDD8B699-A376-47B9-8E2C-18C335AA30F0Q41310309-B5AA32DF-5949-41F6-85F4-64817A342639Q42814267-4A2BDF18-3881-4EF3-B6E9-A67865A6EACAQ42815581-350016B8-BE8E-47EE-A324-228FA7D34BF1Q43831424-61F656CF-E5B7-4922-A4C3-F86FAFFDFEC8Q43968133-80FFA626-314F-4550-B538-8222933E7E80Q52661560-47B9A6CD-2B1B-486A-97AC-D6E5DF317A78Q53417430-6B557169-91F8-41AA-B7ED-7C2AC4F7D11A
P2860
Progression toward tumor cell phenotype is enhanced by overexpression of a mutant p53 tumor-suppressor gene isolated from nasopharyngeal carcinoma.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Progression toward tumor cell ...... from nasopharyngeal carcinoma.
@ast
Progression toward tumor cell ...... from nasopharyngeal carcinoma.
@en
type
label
Progression toward tumor cell ...... from nasopharyngeal carcinoma.
@ast
Progression toward tumor cell ...... from nasopharyngeal carcinoma.
@en
prefLabel
Progression toward tumor cell ...... from nasopharyngeal carcinoma.
@ast
Progression toward tumor cell ...... from nasopharyngeal carcinoma.
@en
P2093
P2860
P356
P1476
Progression toward tumor cell ...... from nasopharyngeal carcinoma.
@en
P2093
P2860
P304
P356
10.1073/PNAS.90.7.2827
P407
P577
1993-04-01T00:00:00Z