Constitutive proteolysis of the ErbB-4 receptor tyrosine kinase by a unique, sequential mechanism.
about
Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signalingHER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cellsThe E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradationErbB4 expression in neural progenitor cells (ST14A) is necessary to mediate neuregulin-1beta1-induced migrationTumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4The type 1 growth factor receptor family: new ligands and receptors and their role in breast cancer.The ins and outs of caveolar signaling. m2 muscarinic cholinergic receptors and eNOS activation versus neuregulin and ErbB4 signaling in cardiac myocytes.The carboxyl terminus of VEGFR-2 is required for PKC-mediated down-regulationAn iron-regulated and glycosylation-dependent proteasomal degradation pathway for the plasma membrane metal transporter ZIP14Deletion of ErbB4 accelerates polycystic kidney disease progression in cpk mice.Transmodulation of cell surface regulatory molecules via ectodomain shedding.Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia.A nuclear variant of ErbB3 receptor tyrosine kinase regulates ezrin distribution and Schwann cell myelination.Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibitionLigand activation leads to regulated intramembrane proteolysis of fibroblast growth factor receptor 3Furin-mediated processing in the early secretory pathway: sequential cleavage and degradation of misfolded insulin receptors.MUC1 is a substrate for gamma-secretaseA structural perspective on the regulation of the epidermal growth factor receptor.Regulation of ErbB-4 endocytosis by neuregulin in GABAergic hippocampal interneurons.Bone microenvironment and androgen status modulate subcellular localization of ErbB3 in prostate cancer cellsErbB4 isoforms selectively regulate growth factor induced Madin-Darby canine kidney cell tubulogenesis.ADAM proteases, ErbB pathways and cancer.c-erbB-4 protein expression in human breast cancerMMP-9 controls Schwann cell proliferation and phenotypic remodeling via IGF-1 and ErbB receptor-mediated activation of MEK/ERK pathway.Bidirectional signaling of ErbB and Eph receptors at synapses.ErbB4 regulates the timely progression of late fetal lung developmentWWP1: a versatile ubiquitin E3 ligase in signaling and diseases.Dissociated presenilin-1 and TACE processing of ErbB4 in lung alveolar type II cell differentiation.Sequential proteolytic processing of an interferon-alpha receptor subunit by TNF-alpha converting enzyme and presenilins.Selective cleavage of ErbB4 by G-protein-coupled gonadotropin-releasing hormone receptor in cultured hypothalamic neurons.Post-translational modification of the interferon gamma receptor alters its stability and signaling.Proteolytic cleavage and phosphorylation of a tumor-associated ErbB4 isoform promote ligand-independent survival and cancer cell growthCharacterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme and of an alternatively translated polypeptide.Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis.Signalling-competent truncated forms of ErbB2 in breast cancer cells: differential regulation by protein kinase C and phosphatidylinositol 3-kinase.Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2.Tyrosine phosphorylation and proteolysis. Pervanadate-induced, metalloprotease-dependent cleavage of the ErbB-4 receptor and amphiregulin.The noncatalytic TrkCNC2 receptor is cleaved by metalloproteases upon neurotrophin-3 stimulation.Relaxin increases ubiquitin-dependent degradation of fibronectin in vitro and ameliorates renal fibrosis in vivo.Ectodomain cleavage of ErbB-4: characterization of the cleavage site and m80 fragment.
P2860
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P2860
Constitutive proteolysis of the ErbB-4 receptor tyrosine kinase by a unique, sequential mechanism.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Constitutive proteolysis of th ...... unique, sequential mechanism.
@ast
Constitutive proteolysis of th ...... unique, sequential mechanism.
@en
type
label
Constitutive proteolysis of th ...... unique, sequential mechanism.
@ast
Constitutive proteolysis of th ...... unique, sequential mechanism.
@en
prefLabel
Constitutive proteolysis of th ...... unique, sequential mechanism.
@ast
Constitutive proteolysis of th ...... unique, sequential mechanism.
@en
P2860
P356
P1476
Constitutive proteolysis of th ...... a unique, sequential mechanism
@en
P2093
G Carpenter
P2860
P304
P356
10.1083/JCB.139.4.995
P407
P577
1997-11-01T00:00:00Z