The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention.
about
The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptideTransthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease?Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretaseExpanding the Repertoire of Biomarkers for Alzheimer's Disease: Targeted and Non-targeted ApproachesCurrent progress of genetically engineered pig models for biomedical researchProfile of gantenerumab and its potential in the treatment of Alzheimer's diseaseAbeta mediated diminution of MTT reduction--an artefact of single cell culture?Alzheimer's disease related markers, cellular toxicity and behavioral deficits induced six weeks after oligomeric amyloid-β peptide injection in ratsFLZ alleviates the memory deficits in transgenic mouse model of Alzheimer's disease via decreasing beta-amyloid production and tau hyperphosphorylationAβ40 modulates GABA(A) receptor α6 subunit expression and rat cerebellar granule neuron maturation through the ERK/mTOR pathwayLoss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease.Pathogenesis of Alzheimer's diseaseCognitive effects of cell-derived and synthetically derived Aβ oligomers.Alzheimer disease models and human neuropathology: similarities and differencesEfavirenz promotes β-secretase expression and increased Aβ1-40,42 via oxidative stress and reduced microglial phagocytosis: implications for HIV associated neurocognitive disorders (HAND).Anti-Amyloid Effects of Small Molecule Aβ-Binding Agents in PS1/APP MiceDeletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo.Protective Effects of Wogonin against Alzheimer's Disease by Inhibition of Amyloidogenic Pathway.The intersection of amyloid beta and tau at synapses in Alzheimer's diseaseTherapeutic approaches to delay the onset of Alzheimer's diseasePrion protein and Abeta-related synaptic toxicity impairment.Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer's amyloid β-peptide elimination from the brainIsolation and characterization of antibody fragments selective for specific protein morphologies from nanogram antigen samples.CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease miceClearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease.APPswe/Aβ regulation of osteoclast activation and RAGE expression in an age-dependent manner.Soluble beta-amyloid peptides, but not insoluble fibrils, have specific effect on neuronal microRNA expression.A generic method for design of oligomer-specific antibodies.Modes of Aβ toxicity in Alzheimer's disease.The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease.Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD)Neurotoxic effects induced by the Drosophila amyloid-beta peptide suggest a conserved toxic function.Anti-aβ oligomer IgG and surface sialic acid in intravenous immunoglobulin: measurement and correlation with clinical outcomes in Alzheimer's disease treatment.Neurovascular and neurometabolic derailment in aging and Alzheimer's disease.VPS35 haploinsufficiency increases Alzheimer's disease neuropathology.CSF levels of oligomeric alpha-synuclein and beta-amyloid as biomarkers for neurodegenerative disease.Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein.Mechanisms of AD neurodegeneration may be independent of Aβ and its derivatives.Dynamics of metastable β-hairpin structures in the folding nucleus of amyloid β-protein.EVALUATION OF HOW CIGARETTE SMOKE IS A DIRECT RISK FACTOR FOR ALZHEIMER'S DISEASE.
P2860
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P2860
The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
The role of cell-derived oligo ...... for therapeutic intervention.
@ast
The role of cell-derived oligo ...... for therapeutic intervention.
@en
type
label
The role of cell-derived oligo ...... for therapeutic intervention.
@ast
The role of cell-derived oligo ...... for therapeutic intervention.
@en
prefLabel
The role of cell-derived oligo ...... for therapeutic intervention.
@ast
The role of cell-derived oligo ...... for therapeutic intervention.
@en
P2093
P356
P1476
The role of cell-derived oligo ...... s for therapeutic intervention
@en
P2093
Fadeeva JV
Podlisny MB
Shankar GM
Townsend M
P304
P356
10.1042/BST20051087
P577
2005-11-01T00:00:00Z