Deletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo. - Wikidata - awgldk - TriplyDB

Deletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo.

Deletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo.

http://www.wikidata.org/entity/Q33793579

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G Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRs An Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase Activity Allosteric modulation of the M1 muscarinic acetylcholine receptor: improving cognition and a potential treatment for schizophrenia and Alzheimer's disease Exome sequencing of case-unaffected-parents trios reveals recessive and de novo genetic variants in sporadic ALS.Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans Revisiting the Role of Acetylcholinesterase in Alzheimer's Disease: Cross-Talk with P-tau and β-Amyloid Tong Luo Jiu Nao ameliorates Aβ1-40-induced cognitive impairment on adaptive behavior learning by modulating ERK/CaMKII/CREB signaling in the hippocampus.Muscarinic Acetylcholine Receptor Subtypes as Potential Drug Targets for the Treatment of Schizophrenia, Drug Abuse and Parkinson's Disease Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo Pre- and post-synaptic cortical cholinergic deficits are proportional to amyloid plaque presence and density at preclinical stages of Alzheimer's disease Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling.Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells.A Systems View of the Differences between APOE ε4 Carriers and Non-carriers in Alzheimer's Disease.Nonvascular retinal imaging markers of preclinical Alzheimer's disease.Cholinergic modulation of amyloid precursor protein processing with emphasis on M1 muscarinic receptor: perspectives and challenges in treatment of Alzheimer's disease.Neuronal receptors as targets for the action of amyloid-beta protein (Aβ) in the brain.Novel disease-modifying therapeutics for the treatment of Alzheimer's disease.Activation of M1 and M4 muscarinic receptors as potential treatments for Alzheimer's disease and schizophrenia M1 muscarinic acetylcholine receptor in Alzheimer's disease Muscarinic acetylcholine receptors: novel opportunities for drug development.Effect of cholinergic signaling on neuronal cell bioenergetics.The Distinct Role of ADAM17 in APP Proteolysis and Microglial Activation Related to Alzheimer's Disease.Cholinergic System and Post-translational Modifications: An Insight on the Role in Alzheimer's Disease Cadmium-induced cell death of basal forebrain cholinergic neurons mediated by muscarinic M1 receptor blockade, increase in GSK-3β enzyme, β-amyloid and tau protein levels.Rejuvenating procholinergic treatments for cognition enhancement in AD: current challenges and future prospects.The Role of ADAM10 in Alzheimer's Disease.Cholinergic Mechanisms in the Cerebral Cortex: Beyond Synaptic Transmission.Scopolamine Impairs Appetitive But Not Aversive Trace Conditioning: Role of the Medial Prefrontal Cortex.Loss of muscarinic M1 receptor exacerbates Alzheimer's disease-like pathology and cognitive decline.Physiological roles of CNS muscarinic receptors gained from knockout mice.Pharmacological effects of Ibuprofen on learning and memory, muscarinic receptors gene expression and APP isoforms level in pre-frontal cortex of AlCl₃-induced toxicity mouse model.Disease-Modifying Effects of M1 Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model.Acute Effects of Muscarinic M1 Receptor Modulation on AβPP Metabolism and Amyloid-β Levels in vivo: A Microdialysis Study.L-Satropane Prevents Retinal Neuron Damage by Attenuating Cell Apoptosis and Aβ Production via Activation of M1 Muscarinic Acetylcholine Receptor.Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology.Effects of sub-chronic donepezil on brain Abeta and cognition in a mouse model of Alzheimer's disease.A specific multi-nutrient formulation enhances M1 muscarinic acetylcholine receptor responses in vitro.The snake venom peptide Bj-PRO-7a is a M1 muscarinic acetylcholine receptor agonist.AMPA-ergic regulation of amyloid-β levels in an Alzheimer's disease mouse model.

P2860

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P2860

Deletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo.

http://www.wikidata.org/entity/Q33793579

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Deletion of M1 muscarinic acet ...... athology in vitro and in vivo.

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Deletion of M1 muscarinic acet ...... athology in vitro and in vivo.

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type

label

Deletion of M1 muscarinic acet ...... athology in vitro and in vivo.

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Deletion of M1 muscarinic acet ...... athology in vitro and in vivo.

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prefLabel

Deletion of M1 muscarinic acet ...... athology in vitro and in vivo.

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Deletion of M1 muscarinic acet ...... athology in vitro and in vivo.

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JNEUROSCI.6393-09.2010

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Journal of Neuroscience

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Deletion of M1 muscarinic acet ...... athology in vitro and in vivo.

@en

P2093

Albert A Davis

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Allan I Levey

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James J Lah

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Jason J Fritz

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Jürgen Wess

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P2860

Alzheimer Disease in the US Population

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

ADAM-10 over-expression increases cortical synaptogenesis

Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

Amyloid precursor protein trafficking, processing, and function

Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers.

The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention.

Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice.

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4190-4196

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10.1523/JNEUROSCI.6393-09.2010

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