Relationship between pore occupancy and gating in BK potassium channels.
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Structural mechanism of C-type inactivation in K(+) channelsBK channels: multiple sensors, one activation gateMolecular interactions involved in proton-dependent gating in KcsA potassium channelsStructural correlates of selectivity and inactivation in potassium channels.Coupling and cooperativity in voltage activation of a limited-state BK channel gating in saturating Ca2+.BK channel activation: structural and functional insightsElectrostatic influences of charged inner pore residues on the conductance and gating of small conductance Ca2+ activated K+ channels.Cysteine scanning and modification reveal major differences between BK channels and Kv channels in the inner pore region.Charge substitution for a deep-pore residue reveals structural dynamics during BK channel gating.Tungstate-targeting of BKαβ1 channels tunes ERK phosphorylation and cell proliferation in human vascular smooth muscle.Selectivity filter gating in large-conductance Ca(2+)-activated K+ channels.Calcium ions open a selectivity filter gate during activation of the MthK potassium channelA mechanistic description of gating of the human cardiac ryanodine receptor in a regulated minimal environment.Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation.Closed state-coupled C-type inactivation in BK channels.Molecular mechanisms of BK channel activation.Unambiguous observation of blocked states reveals altered, blocker-induced, cardiac ryanodine receptor gatingBK channel opening involves side-chain reorientation of multiple deep-pore residues.The BK channel: a vital link between cellular calcium and electrical signaling.The pore structure and gating mechanism of K2P channels.Ca2+ block and flickering both contribute to the negative slope of the IV curve in BK channelsTl+-induced micros gating of current indicates instability of the MaxiK selectivity filter as caused by ion/pore interaction.Saturation and microsecond gating of current indicate depletion-induced instability of the MaxiK selectivity filter.An extracellular domain of the accessory β1 subunit is required for modulating BK channel voltage sensor and gate.Hydrophobic interaction between contiguous residues in the S6 transmembrane segment acts as a stimuli integration node in the BK channel.Molecular Mechanisms Underlying Renin-Angiotensin-Aldosterone System Mediated Regulation of BK ChannelsState-independent block of BK channels by an intracellular quaternary ammonium.Atypical calcium regulation of the PKD2-L1 polycystin ion channel.Fast and slow gating are inherent properties of the pore module of the K+ channel Kcv.Where's the gate? Gating in the deep pore of the BK(Ca) channel.Multiple mechanisms underlying rectification in retinal cyclic nucleotide-gated (CNGA1) channels.BK channel activation by tungstate requires the β1 subunit extracellular loop residues essential to modulate voltage sensor function and channel gating.Site-specific ion occupation in the selectivity filter causes voltage-dependent gating in a viral K+ channel.
P2860
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P2860
Relationship between pore occupancy and gating in BK potassium channels.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Relationship between pore occupancy and gating in BK potassium channels.
@ast
Relationship between pore occupancy and gating in BK potassium channels.
@en
type
label
Relationship between pore occupancy and gating in BK potassium channels.
@ast
Relationship between pore occupancy and gating in BK potassium channels.
@en
prefLabel
Relationship between pore occupancy and gating in BK potassium channels.
@ast
Relationship between pore occupancy and gating in BK potassium channels.
@en
P2860
P356
P1476
Relationship between pore occupancy and gating in BK potassium channels.
@en
P2093
Rebecca A Piskorowski
Richard W Aldrich
P2860
P304
P356
10.1085/JGP.200509482
P577
2006-05-01T00:00:00Z