The location of a closed channel gate in the GABAA receptor channel.
about
Allosteric activation mechanism of the cys-loop receptorsThe dual modulatory effects of efavirenz on GABAA receptors are mediated via two distinct sites.Use of the light-dark box to compare the anxiety-related behavior of virgin and postpartum female rats.X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.Robust photoregulation of GABA(A) receptors by allosteric modulation with a propofol analogue.Structural answers and persistent questions about how nicotinic receptors work.Structure of the M2 transmembrane segment of GLIC, a prokaryotic Cys loop receptor homologue from Gloeobacter violaceus, probed by substituted cysteine accessibility.Binding sites for bilobalide, diltiazem, ginkgolide, and picrotoxinin at the 5-HT3 receptor.5-HT3 receptor ion size selectivity is a property of the transmembrane channel, not the cytoplasmic vestibule portals.Engineering a prokaryotic Cys-loop receptor with a third functional domain.The atypical cation-conduction and gating properties of ELIC underscore the marked functional versatility of the pentameric ligand-gated ion-channel fold.Gating-induced conformational rearrangement of the γ-aminobutyric acid type A receptor β-α subunit interface in the membrane-spanning domainModular design of Cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loopAssessment of subunit-dependent direct gating and allosteric modulatory effects of carisoprodol at GABA(A) receptors.Bubbles, gating, and anesthetics in ion channelsThe insecticide fipronil and its metabolite fipronil sulphone inhibit the rat alpha1beta2gamma2L GABA(A) receptor.GABA-induced intersubunit conformational movement in the GABAA receptor alpha 1M1-beta 2M3 transmembrane subunit interface: experimental basis for homology modeling of an intravenous anesthetic binding site.Using molecular dynamics to elucidate the structural basis for function in pLGICsBrain regional distribution of GABA(A) receptors exhibiting atypical GABA agonism: roles of receptor subunits.Atomic structure and dynamics of pentameric ligand-gated ion channels: new insight from bacterial homologues.The structural basis of function in Cys-loop receptors.A novel GABA(A) receptor pharmacology: drugs interacting with the α(+) β(-) interface.Discriminating between 5-HT₃A and 5-HT₃AB receptorsInfluences on blockade by t-butylbicyclo-phosphoro-thionate of GABA(A) receptor spontaneous gating, agonist activation and desensitization.The desensitization gate of inhibitory Cys-loop receptors.Agonist- and antagonist-induced conformational changes of loop F and their contributions to the rho1 GABA receptor function.Inhibitory effects of insulin on GABAA currents modulated by the GABAA alpha subunit.String method solution of the gating pathways for a pentameric ligand-gated ion channel.Side chain flexibility and the pore dimensions in the GABAA receptor.
P2860
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P2860
The location of a closed channel gate in the GABAA receptor channel.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
The location of a closed channel gate in the GABAA receptor channel.
@ast
The location of a closed channel gate in the GABAA receptor channel.
@en
type
label
The location of a closed channel gate in the GABAA receptor channel.
@ast
The location of a closed channel gate in the GABAA receptor channel.
@en
prefLabel
The location of a closed channel gate in the GABAA receptor channel.
@ast
The location of a closed channel gate in the GABAA receptor channel.
@en
P2860
P356
P1476
The location of a closed channel gate in the GABAA receptor channel
@en
P2093
P2860
P304
P356
10.1085/JGP.200609639
P577
2007-01-16T00:00:00Z