about
Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorptionBalance of activity between LN(v)s and glutamatergic dorsal clock neurons promotes robust circadian rhythms in DrosophilaChannel opening by anesthetics and GABA induces similar changes in the GABAA receptor M2 segmentProbing the multifactorial basis of Plasmodium falciparum quinine resistance: Evidence for a strain-specific contribution of the sodium-proton exchanger PfNHEMalaria parasite type 4 equilibrative nucleoside transporters (ENT4) are purine transporters with distinct substrate specificityChloroquine-resistant isoforms of the Plasmodium falciparum chloroquine resistance transporter acidify lysosomal pH in HEK293 cells more than chloroquine-sensitive isoforms.Length and amino acid sequence of peptides substituted for the 5-HT3A receptor M3M4 loop may affect channel expression and desensitizationIdentification of cystic fibrosis transmembrane conductance regulator channel-lining residues in and flanking the M6 membrane-spanning segment.Interaction of picrotoxin with GABAA receptor channel-lining residues probed in cysteine mutants.Gamma-aminobutyric acid increases the water accessibility of M3 membrane-spanning segment residues in gamma-aminobutyric acid type A receptorsAcetylcholine receptor channel structure probed in cysteine-substitution mutants.GABAA receptor structure-function studies: a reexamination in light of new acetylcholine receptor structures.Rodent intestinal folate transporters (SLC46A1): secondary structure, functional properties, and response to dietary folate restriction.Structure of the M2 transmembrane segment of GLIC, a prokaryotic Cys loop receptor homologue from Gloeobacter violaceus, probed by substituted cysteine accessibility.5-HT3 receptor ion size selectivity is a property of the transmembrane channel, not the cytoplasmic vestibule portals.Purine import into malaria parasites as a target for antimalarial drug development.Yeast-based high-throughput screen identifies Plasmodium falciparum equilibrative nucleoside transporter 1 inhibitors that kill malaria parasitesAre MD-PhD programs meeting their goals? An analysis of career choices made by graduates of 24 MD-PhD programs.Gating-induced conformational rearrangement of the γ-aminobutyric acid type A receptor β-α subunit interface in the membrane-spanning domainEmerging molecular mechanisms of general anesthetic action.The location of a closed channel gate in the GABAA receptor channel.Locating the anion-selectivity filter of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel.Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug developmentSubstrate and Inhibitor Specificity of the Plasmodium berghei Equilibrative Nucleoside Transporter Type 1Using molecular dynamics to elucidate the structural basis for function in pLGICsUV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells.Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1.Cysteine Modification: Probing Channel Structure, Function and Conformational Change.A role for the beta 1-beta 2 loop in the gating of 5-HT3 receptors.Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins.Probing the structural and functional domains of the CFTR chloride channel.Erythrocytic adenosine monophosphate as an alternative purine source in Plasmodium falciparum.Structural and electrostatic properties of the 5-HT3 receptor pore revealed by substituted cysteine accessibility mutagenesis.State-dependent cross-linking of the M2 and M3 segments: functional basis for the alignment of GABAA and acetylcholine receptor M3 segments.Taking Charge: Feeding Malaria via Anion Channels.Evidence for distinct conformations of the two alpha 1 subunits in diazepam-bound GABA(A) receptors.A bitter substance induces a rise in intracellular calcium in a subpopulation of rat taste cells.GABA(A) receptor M2-M3 loop secondary structure and changes in accessibility during channel gating.Defining the propofol binding site location on the GABAA receptor.Na+/Ca2+ exchange inhibitors: potential drugs to mitigate the severity of ischemic injury.
P50
Q24320048-6B2ED055-67F3-4B84-85B0-14C73FF6BA9BQ24616479-DBE28648-1D32-4230-A508-DD6A02864A95Q24683541-28371377-220B-48A1-8CD6-9624BB22506FQ27861959-0F0D4B74-8EAB-4C96-81CD-D8F053FFD012Q27974769-987F76DD-7E69-41A0-BAF3-37D714998EBCQ30357176-59D7B480-844C-4585-8C00-07DBC7B0586BQ31060057-BAEDC954-DCD9-49C8-9C64-18BD67657D4CQ34017913-A28A18C1-7010-4078-8861-679121F58EAEQ34047528-908FA79C-EC74-4204-9D79-E07BC4CAE859Q34171714-7E78E93C-AFAA-4CDF-A220-D6D7EE25C8F2Q34250941-97580FDC-BFB0-46B6-A496-F1A336021414Q34365717-EAA2A7CF-8556-4300-80D3-4A267558D3AEQ34693868-9CBDBAA7-BA3D-4077-83D2-FF3472D39BC4Q34800089-87812544-D11F-40A2-93E8-CB99899393B1Q35238474-65E9623E-5F52-4B8C-9AD0-DE018FBE0B43Q35513431-97A81207-400B-480E-9E99-CE01FB41A163Q35545065-47A37E15-D885-46F1-B6B1-24FD40326732Q35636848-97541DD3-53AC-4A2E-928B-D52A460C7F48Q36201884-F8D33196-BD98-4661-BBFF-45F0DC60225BQ36242467-3482B390-1759-4005-BD98-E80398C1F3CAQ36299672-69E4BCC7-0FD1-46E0-9DF3-96247F11A911Q36411911-2571EF3E-78CE-4527-BC10-D9E8306C4144Q36446094-3C78F073-A6CC-4D70-BF99-0D8522C46D61Q36947737-77A857C2-D93E-4F9B-82F5-BE6210F01115Q37240694-0F60E6CC-C33E-4E85-9D9C-AACE3C28B6EAQ37311917-C7527CBB-E5D6-4709-9716-A0D417D77138Q37439211-17C64217-5155-4452-B3F6-20CCABECE851Q38588680-C77FCE7F-6A70-430A-9FC8-06154A671F8BQ40362619-511B2E34-489A-454C-A9DE-C9D8B862F807Q41142209-5CEB4699-4315-47B4-9BB0-FA280A383872Q41725516-25CE3FB2-BC4F-4A2E-95AC-63A7B51448AEQ41817367-4920CFB8-9D8E-4E43-97CC-BEC6826F31D9Q42659707-BB08D612-C2BC-4C19-B1E9-489B805F5AF6Q42684049-00BE4B4F-7E68-4A9F-BF99-6E4C63E813B1Q43623297-F3A8DAA0-7DC5-461C-B15B-1441FE770756Q43757149-59757F0A-33CD-44AC-A002-CE41140269F6Q43892118-83CC4683-5C96-4ECD-B607-89ED322A9CB9Q44133863-DFB233B9-AC9E-4DCA-83B8-693125EFC1B5Q44727242-0F737329-989B-474D-847B-5D9A30BB58F4Q44949009-5C40D669-11A2-49FE-A8F1-175B2600F14E
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Myles H Akabas
@es
Myles H. Akabas
@en
Myles H. Akabas
@nl
Myles H. Akabas
@sl
type
label
Myles H Akabas
@es
Myles H. Akabas
@en
Myles H. Akabas
@nl
Myles H. Akabas
@sl
prefLabel
Myles H Akabas
@es
Myles H. Akabas
@en
Myles H. Akabas
@nl
Myles H. Akabas
@sl
P106
P1153
7006021457
P21
P31
P496
0000-0001-8781-7846
P569
2000-01-01T00:00:00Z