A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway
about
The transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expressionStriatal microRNA controls cocaine intake through CREB signallingCreb coactivators direct anabolic responses and enhance performance of skeletal muscleDistinct roles of DBHS family members in the circadian transcriptional feedback loopActivation of TORC1 transcriptional coactivator through MEKK1-induced phosphorylationNight/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling.Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defectsPotent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screeningp54nrb is a transcriptional corepressor of the progesterone receptor that modulates transcription of the labor-associated gene, connexin 43 (Gja1).Rasd1 modulates the coactivator function of NonO in the cyclic AMP pathway.CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvement.CREB and the CRTC co-activators: sensors for hormonal and metabolic signalsThe p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.NONO couples the circadian clock to the cell cycleThe DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffoldGlucocorticoid induction of occludin expression and endothelial barrier requires transcription factor p54 NONOp54nrb/NONO regulates cyclic AMP-dependent glucocorticoid production by modulating phosphodiesterase mRNA splicing and degradation.Paraspeckle protein 1 (PSPC1) is involved in the cisplatin induced DNA damage response--role in G1/S checkpoint.Calcineurin mediates the gonadotropin-releasing hormone effect on expression of both subunits of the follicle-stimulating hormone through distinct mechanisms.Pro-oncogenic Roles of HLXB9 Protein in Insulinoma Cells through Interaction with Nono Protein and Down-regulation of the c-Met Inhibitor Cblb (Casitas B-lineage Lymphoma b).EBV noncoding RNA EBER2 interacts with host RNA-binding proteins to regulate viral gene expression.Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth.The coactivator CRTC1 promotes cell proliferation and transformation via AP-1The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.Complex assembly on the human CYP17 promoter.Paraspeckles: nuclear bodies built on long noncoding RNABipartite functions of the CREB co-activators selectively direct alternative splicing or transcriptional activationThe transcription-splicing protein NonO/p54nrb and three NonO-interacting proteins bind to distal enhancer region and augment rhodopsin expression.Gonadotrophin-releasing hormone signalling downstream of calmodulin.Circadian clock disruptions and the risk of cancer.Small G Proteins Dexras1 and RHES and Their Role in Pathophysiological Processes.Computational genomic analysis of PARK7 interactome reveals high BBS1 gene expression as a prognostic factor favoring survival in malignant pleural mesothelioma.Tyrosine Residues Regulate Multiple Nuclear Functions of P54nrb.Transcriptional regulators form diverse groups with context-dependent regulatory functions.Subnuclear re-localization of SOX10 and p54NRB correlates with a unique neurological phenotype associated with SOX10 missense mutations.A single cell level measurement of StAR expression and activity in adrenal cells.Deregulation of CRTCs in Aging and Age-Related Disease Risk.Consensus PP1 binding motifs regulate transcriptional corepression and alternative RNA splicing activities of the steroid receptor coregulators, p54nrb and PSF.Circadian Dexras1 in rats: Development, location and responsiveness to light.
P2860
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P2860
A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
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2007年學術文章
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2007年學術文章
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name
A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway
@ast
A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway
@en
type
label
A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway
@ast
A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway
@en
prefLabel
A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway
@ast
A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway
@en
P2093
P2860
P356
P1476
A coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway
@en
P2093
Anthony P Orth
Antonio L Amelio
Becky A Mercer
Jennifer Busby
John B Hogenesch
Juliana J Conkright
Loren J Miraglia
Michael D Conkright
Valerie Cavett
P2860
P304
20314-20319
P356
10.1073/PNAS.0707999105
P407
P50
P577
2007-12-11T00:00:00Z