Ablation of beta1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation.
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Mammary gland developmentA tale of two collagen receptors, integrin β1 and discoidin domain receptor 1, in epithelial cell differentiationβ1 and β4 integrins: from breast development to clinical practiceActin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary glandCrosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud developmentThe ECM protein nephronectin promotes kidney development via integrin alpha8beta1-mediated stimulation of Gdnf expressionIntegrins as architects of cell behaviorConditional knockout of fibronectin abrogates mouse mammary gland lobuloalveolar differentiation.Extracellular matrix control of mammary gland morphogenesis and tumorigenesis: insights from imaging.Integrins in development and cancer.Structural and mechanical functions of integrins.Functional interactions between 17 β -estradiol and progesterone regulate autophagy during acini formation by bovine mammary epithelial cells in 3D culturesOvarian hormones are not required for PRL-induced mammary tumorigenesis, but estrogen enhances neoplastic processesIntegrin signaling through FAK in the regulation of mammary stem cells and breast cancerCellular microenvironment influences the ability of mammary epithelia to undergo cell cycle.Cell-matrix interactions in mammary gland development and breast cancerDystroglycan controls signaling of multiple hormones through modulation of STAT5 activity.Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cellsDystroglycan loss disrupts polarity and beta-casein induction in mammary epithelial cells by perturbing laminin anchoring.Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progressionIntegrins regulate epithelial cell differentiation by modulating Notch activity.ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.Laminin regulates PI3K basal localization and activation to sustain STAT5 activation.Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization.The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium.Keratin 6 is not essential for mammary gland development.The mammary gland microenvironment directs progenitor cell fate in vivoGene transcriptional networks integrate microenvironmental signals in human breast cancerIntegrated extracellular matrix signaling in mammary gland development and breast cancer progression.The C terminus of talin links integrins to cell cycle progression.Integrin α3β1 as a breast cancer targetBreast cancer cell migration is regulated through junctional adhesion molecule-A-mediated activation of Rap1 GTPase.Dynamic reciprocity between cells and their microenvironment in reproduction.Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer.Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function.β1-integrins signaling and mammary tumor progression in transgenic mouse models: implications for human breast cancer.Microenvironmental control of the breast cancer cell cycle.Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype.Reprogramming non-mammary and cancer cells in the developing mouse mammary glandSpecific β-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells.
P2860
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P2860
Ablation of beta1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Ablation of beta1 integrin in ...... hogenesis and differentiation.
@ast
Ablation of beta1 integrin in ...... hogenesis and differentiation.
@en
type
label
Ablation of beta1 integrin in ...... hogenesis and differentiation.
@ast
Ablation of beta1 integrin in ...... hogenesis and differentiation.
@en
prefLabel
Ablation of beta1 integrin in ...... hogenesis and differentiation.
@ast
Ablation of beta1 integrin in ...... hogenesis and differentiation.
@en
P2093
P2860
P356
P1476
Ablation of beta1 integrin in ...... phogenesis and differentiation
@en
P2093
Charles H Streuli
Elise Lambert
Emma T Lowe
Franziska Schatzmann
Günther Schüetz
Julia Cheung
Matthew J Naylor
Nancy E Hynes
Pengbo Wang
P2860
P304
P356
10.1083/JCB.200503144
P407
P577
2005-11-01T00:00:00Z