The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line
about
Identification of a TPX2-like microtubule-associated protein in DrosophilaIdentification of genes that promote or antagonize somatic homolog pairing using a high-throughput FISH-based screenKinesin-5: cross-bridging mechanism to targeted clinical therapyFunctional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interferenceA minus-end-directed kinesin with plus-end tracking protein activity is involved in spindle morphogenesisRecruitment of MKLP1 to the spindle midzone/midbody by INCENP is essential for midbody formation and completion of cytokinesis in human cellsCell cycle-dependent dynamics and regulation of mitotic kinesins in Drosophila S2 cellsMechanistic analysis of the mitotic kinesin Eg5.Monastrol inhibition of the mitotic kinesin Eg5.RNA interference-mediated silencing of mitotic kinesin KIF14 disrupts cell cycle progression and induces cytokinesis failure.Cell cycle-dependent translocation of PRC1 on the spindle by Kif4 is essential for midzone formation and cytokinesis.Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formationGenes required for mitotic spindle assembly in Drosophila S2 cellsDrosophila CLASP is required for the incorporation of microtubule subunits into fluxing kinetochore fibresThe kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignmentKinetochore-driven formation of kinetochore fibers contributes to spindle assembly during animal mitosisHuman chromokinesin KIF4A functions in chromosome condensation and segregationThe KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAKSpindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochoreFunctional importance of the anaphase-promoting complex-Cdh1-mediated degradation of TMAP/CKAP2 in regulation of spindle function and cytokinesis.Rho-kinase controls cell shape changes during cytokinesisParallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targetsRNAi and the shape of things to comeFunctional genomics of cell morphology using RNA interference: pick your style, broad or deepDynein/dynactin regulate metaphase spindle length by targeting depolymerizing activities to spindle poles.Recruitment of Polo kinase to the spindle midzone during cytokinesis requires the Feo/Klp3A complexA second tubulin binding site on the kinesin-13 motor head domain is important during mitosisAn Asp-CaM complex is required for centrosome-pole cohesion and centrosome inheritance in neural stem cellsMicrocephaly protein Asp focuses the minus ends of spindle microtubules at the pole and within the spindleS. pombe kinesins-8 promote both nucleation and catastrophe of microtubulesCYK4 promotes antiparallel microtubule bundling by optimizing MKLP1 neck conformationHeterochromatic threads connect oscillating chromosomes during prometaphase I in Drosophila oocytesKebab: kinetochore and EB1 associated basic protein that dynamically changes its localisation during Drosophila mitosisDual role of topoisomerase II in centromere resolution and aurora B activityATPase Cycle of the Nonmotile Kinesin NOD Allows Microtubule End Tracking and Drives Chromosome MovementInsight into the molecular mechanism of the multitasking kinesin-8 motorThe kinesin-8 Kip3 scales anaphase spindle length by suppression of midzone microtubule polymerization.Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle.Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner.Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments
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P2860
The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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name
The roles of microtubule-based ...... in the Drosophila S2 cell line
@ast
The roles of microtubule-based ...... in the Drosophila S2 cell line
@en
type
label
The roles of microtubule-based ...... in the Drosophila S2 cell line
@ast
The roles of microtubule-based ...... in the Drosophila S2 cell line
@en
prefLabel
The roles of microtubule-based ...... in the Drosophila S2 cell line
@ast
The roles of microtubule-based ...... in the Drosophila S2 cell line
@en
P2860
P356
P1476
The roles of microtubule-based ...... in the Drosophila S2 cell line
@en
P2093
Gohta Goshima
Ronald D Vale
P2860
P304
P356
10.1083/JCB.200303022
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P577
2003-09-01T00:00:00Z