Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities.
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Identification of a novel functional JAK1 S646P mutation in acute lymphoblastic leukemia.Molecular basis of targeted therapy in T/NK-cell lymphoma/leukemia: A comprehensive genomic and immunohistochemical analysis of a panel of 33 cell linesGenome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemiaMutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia.JAK-STAT-mediated chronic inflammation impairs cytotoxic T lymphocyte activation to decrease anti-PD-1 immunotherapy efficacy in pancreatic cancer.HiJAKing the epigenome in leukemia and lymphoma.Nuclear Import of JAK1 Is Mediated by a Classical NLS and Is Required for Survival of Diffuse Large B-cell Lymphoma.Mutant JAK3 signaling is increased by loss of wild type JAK3 or by acquiring secondary JAK3 mutations in T-ALL.
P2860
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P2860
Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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name
Distinct Acute Lymphoblastic L ...... d JAK Inhibitor Specificities.
@ast
Distinct Acute Lymphoblastic L ...... d JAK Inhibitor Specificities.
@en
type
label
Distinct Acute Lymphoblastic L ...... d JAK Inhibitor Specificities.
@ast
Distinct Acute Lymphoblastic L ...... d JAK Inhibitor Specificities.
@en
prefLabel
Distinct Acute Lymphoblastic L ...... d JAK Inhibitor Specificities.
@ast
Distinct Acute Lymphoblastic L ...... d JAK Inhibitor Specificities.
@en
P2093
P2860
P50
P356
P1476
Distinct Acute Lymphoblastic L ...... d JAK Inhibitor Specificities.
@en
P2093
Elisabeth Losdyck
Elisabetta Flex
Laurent Knoops
Lorraine Springuel
Olga Gielen
Sandrine Degryse
Tekla Hornakova
P2860
P304
29022-29034
P356
10.1074/JBC.M115.670224
P407
P577
2015-10-07T00:00:00Z