Characterization of hematopoietic progenitor cells that express the transcription factor SCL, using a lacZ "knock-in" strategy
about
A critical role for the transcription factor Scl in platelet production during stress thrombopoiesisLMO4 controls the balance between excitatory and inhibitory spinal V2 interneuronsMegakaryocyte biology and related disordersSOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardationFunctional analysis of Asb-1 using genetic modification in miceAdult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survivalDisordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient miceThe critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12The TAL1/SCL transcription factor regulates cell cycle progression and proliferation in differentiating murine bone marrow monocyte precursorsThe essential haematopoietic transcription factor Scl is also critical for neuronal developmentSCL/Tal-1 is essential for hematopoietic commitment of the hemangioblast but not for its developmentCombinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouseGenetic deletion of murine SPRY domain-containing SOCS box protein 2 (SSB-2) results in very mild thrombocytopeniaDifferential adhesion molecule expression during murine embryonic stem cell commitment to the hematopoietic and endothelial lineages.Origin of hematopoietic progenitors during embryogenesis.Retrotransposon insertion in the T-cell acute lymphocytic leukemia 1 (Tal1) gene is associated with severe renal disease and patchy alopecia in Hairpatches (Hpt) mice.Suppressor of cytokine signaling-1 regulates acute inflammatory arthritis and T cell activation.Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells.In vivo evolution of metabolic pathways: Assembling old parts to build novel and functional structuresDeletion of the Scl +19 enhancer increases the blood stem cell compartment without affecting the formation of mature blood lineages.The scl +18/19 stem cell enhancer is not required for hematopoiesis: identification of a 5' bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1Lineage development of hematopoietic stem and progenitor cells.Genetic interaction between Kit and Scl.SCL assembles a multifactorial complex that determines glycophorin A expression.Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia geneResolving early mesoderm diversification through single-cell expression profilingProtein stability and transcription factor complex assembly determined by the SCL-LMO2 interaction.Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene.Analysis of the advantages of cis reporters in optimized FACS-Gal.A novel reporter strain to follow Cre-mediated recombination in T and NK cells.
P2860
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P2860
Characterization of hematopoietic progenitor cells that express the transcription factor SCL, using a lacZ "knock-in" strategy
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Characterization of hematopoie ...... ing a lacZ "knock-in" strategy
@ast
Characterization of hematopoie ...... ing a lacZ "knock-in" strategy
@en
type
label
Characterization of hematopoie ...... ing a lacZ "knock-in" strategy
@ast
Characterization of hematopoie ...... ing a lacZ "knock-in" strategy
@en
prefLabel
Characterization of hematopoie ...... ing a lacZ "knock-in" strategy
@ast
Characterization of hematopoie ...... ing a lacZ "knock-in" strategy
@en
P2093
P2860
P356
P1476
Characterization of hematopoie ...... ing a lacZ "knock-in" strategy
@en
P2093
P2860
P304
11897-11902
P356
10.1073/PNAS.95.20.11897
P407
P50
P577
1998-09-01T00:00:00Z