Cytosolic phospholipase A2 is essential for both the immediate and the delayed phases of eicosanoid generation in mouse bone marrow-derived mast cells
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VEGF stimulation of endothelial cell PAF synthesis is mediated by group V 14 kDa secretory phospholipase A2The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptorsLow molecular weight group IIA and group V phospholipase A(2) enzymes have different intracellular locations in mouse bone marrow-derived mast cellsNonsteroidal anti-inflammatory drugs suppress T-cell activation by inhibiting p38 MAPK inductionEpidermal growth factor induces p11 gene and protein expression and down-regulates calcium ionophore-induced arachidonic acid release in human epithelial cellsThe role of phospholipases A2 in schizophreniaTherapies targeting lipid peroxidation in traumatic brain injuryA novel group of phospholipase A2s preferentially expressed in type 2 helper T cellsAn essential role of the Jak-2/STAT-3/cytosolic phospholipase A(2) axis in platelet-derived growth factor BB-induced vascular smooth muscle cell motilitycPGES/p23 is required for glucocorticoid receptor function and embryonic growth but not prostaglandin E2 synthesisDeletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesisA decrease in remodeling accounts for the accumulation of arachidonic acid in murine mast cells undergoing apoptosis.Phospholipase A/Acyltransferase enzyme activity of H-rev107 inhibits the H-RAS signaling pathwayPhospholipase A2 enzymes in eicosanoid generation.Role of group V phospholipase A2 in zymosan-induced eicosanoid generation and vascular permeability revealed by targeted gene disruption.Cytosolic phospholipase A2 alpha amplifies early cyclooxygenase-2 expression, oxidative stress and MAP kinase phosphorylation after cerebral ischemia in mice.Estrogen potentiates the combined effects of transforming growth factor-beta and tumor necrosis factor-alpha on adult human osteoblast-like cell prostaglandin E2 biosynthesisGenetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotypeExpression and function of phospholipase A(2) in brain.The metabolic serine hydrolases and their functions in mammalian physiology and disease.Analysis of two major intracellular phospholipases A(2) (PLA(2)) in mast cells reveals crucial contribution of cytosolic PLA(2)α, not Ca(2+)-independent PLA(2)β, to lipid mobilization in proximal mast cells and distal fibroblasts.Regulation of cytosolic phospholipase A2 (cPLA2alpha) and its association with cell proliferation in human lens epithelial cellsGroup V secretory phospholipase A2 amplifies the induction of cyclooxygenase 2 and delayed prostaglandin D2 generation in mouse bone marrow culture-derived mast cells in a strain-dependent mannerCytosolic phospholipase A(2) alpha mediates electrophysiologic responses of hippocampal pyramidal neurons to neurotoxic NMDA treatmentCytosolic phospholipase A₂: physiological function and role in disease.Group V secretory PLA2 regulates TLR2-dependent eicosanoid generation in mouse mast cells through amplification of ERK and cPLA2alpha activation.Competition and allostery govern substrate selectivity of cyclooxygenase-2.G protein-coupled receptors and the modification of FcepsilonRI-mediated mast cell activation.Group IVA phospholipase A₂ optimizes ovulation and fertilization in rodents through induction of and metabolic coupling with prostaglandin endoperoxide synthase 2.An essential role of cytosolic phospholipase A2alpha in prostaglandin E2-mediated bone resorption associated with inflammationDiscrete role for cytosolic phospholipase A(2)alpha in platelets: studies using single and double mutant mice of cytosolic and group IIA secretory phospholipase A(2).Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidaseLipid profiling reveals arachidonate deficiency in RAW264.7 cells: Structural and functional implications.Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation.Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages.Characterization of eicosanoid synthesis in a genetic ablation model of ceramide kinaseRegulation of Wnt/beta-catenin pathway by cPLA2alpha and PPARdeltaCytosolic phospholipase A2-alpha: a potential therapeutic target for prostate cancerThe role of sphingosine-1-phosphate and its receptors in asthma.The role of G protein-coupled receptors in mast cell activation by antimicrobial peptides: is there a connection?
P2860
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P2860
Cytosolic phospholipase A2 is essential for both the immediate and the delayed phases of eicosanoid generation in mouse bone marrow-derived mast cells
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Cytosolic phospholipase A2 is ...... bone marrow-derived mast cells
@ast
Cytosolic phospholipase A2 is ...... bone marrow-derived mast cells
@en
type
label
Cytosolic phospholipase A2 is ...... bone marrow-derived mast cells
@ast
Cytosolic phospholipase A2 is ...... bone marrow-derived mast cells
@en
prefLabel
Cytosolic phospholipase A2 is ...... bone marrow-derived mast cells
@ast
Cytosolic phospholipase A2 is ...... bone marrow-derived mast cells
@en
P2093
P2860
P356
P1476
Cytosolic phospholipase A2 is ...... bone marrow-derived mast cells
@en
P2093
A Sapirstein
C O Bingham
H Fujishima
J V Bonventre
K F Austen
R O Sanchez Mejia
P2860
P304
P356
10.1073/PNAS.96.9.4803
P407
P577
1999-04-01T00:00:00Z