Bloom's syndrome protein, BLM, colocalizes with replication protein A in meiotic prophase nuclei of mammalian spermatocytes.
about
Nuclear structure in normal and Bloom syndrome cellsReplication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activityPotent inhibition of werner and bloom helicases by DNA minor groove binding drugsRegulation and localization of the Bloom syndrome protein in response to DNA damageMus81 endonuclease localizes to nucleoli and to regions of DNA damage in human S-phase cellsTelomeric D-loops containing 8-oxo-2'-deoxyguanosine are preferred substrates for Werner and Bloom syndrome helicases and are bound by POT1Cell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicaseFancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in miceRECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenanceThe yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci.Localization of the Bloom syndrome helicase to punctate nuclear structures and the nuclear matrix and regulation during the cell cycle: comparison with the Werner's syndrome helicase.MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis.The Arabidopsis BLAP75/Rmi1 homologue plays crucial roles in meiotic double-strand break repair.DNA polymerase beta is critical for mouse meiotic synapsis.Mammalian BLM helicase is critical for integrating multiple pathways of meiotic recombinationSgs1 helicase activity is required for mitotic but apparently not for meiotic functions.RecQ helicases: at the heart of genetic stability.Regulation of meiotic recombination and prophase I progression in mammals.Immunofluorescent characterization of meiotic recombination in human males with variable spermatogenesis.The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities.Meiotic recombination and spatial proximity in the etiology of the recurrent t(11;22)Nucleotide excision repair in rat male germ cells: low level of repair in intact cells contrasts with high dual incision activity in vitroRoles of RecQ family helicases in the maintenance of genome stability.RecQ helicases: suppressors of tumorigenesis and premature aging.Multiple functions of Drosophila BLM helicase in maintenance of genome stability.Recombination nodules in plants.Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stabilityBloom syndrome helicase in meiosis: Pro-crossover functions of an anti-crossover protein.Meiotic defects and decreased expression of genes located around the chromosomal breakpoint in the testis of a patient with a novel 46,X,t(Y;1)(p11.3;p31) translocation
P2860
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P2860
Bloom's syndrome protein, BLM, colocalizes with replication protein A in meiotic prophase nuclei of mammalian spermatocytes.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Bloom's syndrome protein, BLM, ...... ei of mammalian spermatocytes.
@ast
Bloom's syndrome protein, BLM, ...... ei of mammalian spermatocytes.
@en
type
label
Bloom's syndrome protein, BLM, ...... ei of mammalian spermatocytes.
@ast
Bloom's syndrome protein, BLM, ...... ei of mammalian spermatocytes.
@en
prefLabel
Bloom's syndrome protein, BLM, ...... ei of mammalian spermatocytes.
@ast
Bloom's syndrome protein, BLM, ...... ei of mammalian spermatocytes.
@en
P2093
P2860
P356
P1476
Bloom's syndrome protein, BLM, ...... ei of mammalian spermatocytes.
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.10.5622
P407
P577
1999-05-01T00:00:00Z