Small cortical thymocytes are subject to positive selection.
about
Two distinct pathways of positive selection for thymocytes.Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytesInhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cellsLineage commitment in the thymus: only the most differentiated (TCRhibcl-2hi) subset of CD4+CD8+ thymocytes has selectively terminated CD4 or CD8 synthesis.Polarity gene discs large homolog 1 regulates the generation of memory T cells.From stem cells to lymphocytes: biology and transplantation.Identification of a late stage of small noncycling pTalpha- pre-T cells as immediate precursors of T cell receptor alpha/beta+ thymocytes.Stochastic coreceptor shut-off is restricted to the CD4 lineage maturation pathway.Asynchronous coreceptor downregulation after positive thymic selection: prolonged maintenance of the double positive state in CD8 lineage differentiation due to sustained biosynthesis of the CD4 coreceptor.Thymic selection and cell division.
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P2860
Small cortical thymocytes are subject to positive selection.
description
1994 nî lūn-bûn
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1994年の論文
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1994年学术文章
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1994年学术文章
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1994年学术文章
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1994年学术文章
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1994年学术文章
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1994年學術文章
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1994年學術文章
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1994年學術文章
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name
Small cortical thymocytes are subject to positive selection.
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Small cortical thymocytes are subject to positive selection.
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type
label
Small cortical thymocytes are subject to positive selection.
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Small cortical thymocytes are subject to positive selection.
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prefLabel
Small cortical thymocytes are subject to positive selection.
@ast
Small cortical thymocytes are subject to positive selection.
@en
P2860
P356
P1476
Small cortical thymocytes are subject to positive selection.
@en
P2093
Lundberg K
Shortman K
P2860
P304
P356
10.1084/JEM.179.5.1475
P407
P577
1994-05-01T00:00:00Z