Constitutive CD8 expression allows inefficient maturation of CD4+ helper T cells in class II major histocompatibility complex mutant mice.
about
Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice.Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytesHuman CD8 transgene regulation of HLA recognition by murine T cells.The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells.Lineage commitment in the thymus: only the most differentiated (TCRhibcl-2hi) subset of CD4+CD8+ thymocytes has selectively terminated CD4 or CD8 synthesis.Role of the transcription factor Th-POK in CD4:CD8 lineage commitment.Visualization of CD4/CD8 T cell commitment.Role of coreceptors in positive selection and lineage commitment.CD4/CD8 lineage commitment: back to instruction?Stochastic coreceptor shut-off is restricted to the CD4 lineage maturation pathway.T-cell fate.Deletion of the CD4 silencer element supports a stochastic mechanism of thymocyte lineage commitment.A molecular chart of thymocyte positive selection.
P2860
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P2860
Constitutive CD8 expression allows inefficient maturation of CD4+ helper T cells in class II major histocompatibility complex mutant mice.
description
1994 nî lūn-bûn
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1994年の論文
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1994年学术文章
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1994年学术文章
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1994年学术文章
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1994年学术文章
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1994年学术文章
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1994年學術文章
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1994年學術文章
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1994年學術文章
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name
Constitutive CD8 expression al ...... atibility complex mutant mice.
@ast
Constitutive CD8 expression al ...... atibility complex mutant mice.
@en
type
label
Constitutive CD8 expression al ...... atibility complex mutant mice.
@ast
Constitutive CD8 expression al ...... atibility complex mutant mice.
@en
prefLabel
Constitutive CD8 expression al ...... atibility complex mutant mice.
@ast
Constitutive CD8 expression al ...... atibility complex mutant mice.
@en
P2093
P2860
P356
P1476
Constitutive CD8 expression al ...... atibility complex mutant mice.
@en
P2093
P2860
P304
P356
10.1084/JEM.179.6.1997
P407
P577
1994-06-01T00:00:00Z