Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes
about
ICA 512, an autoantigen of type I diabetes, is an intrinsic membrane protein of neurosecretory granulesIdentification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65).Monitoring of antigen-specific CD8 T cells in patients with type 1 diabetes treated with antiCD3 monoclonal antibodiesPre-existing autoimmunity determines type 1 diabetes outcome after Flt3-ligand treatment.Recognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients.Incidental CD8 T cell reactivity against caspase-cleaved apoptotic self-antigens from ubiquitously expressed proteins in islets from prediabetic human leucocyte antigen-A2 transgenic non-obese diabetic mice.Simultaneous detection of circulating autoreactive CD8+ T-cells specific for different islet cell-associated epitopes using combinatorial MHC multimers.Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitusKiller artificial antigen-presenting cells: the synthetic embodiment of a 'guided missile'.Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetesDemonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients.Sidechain biology and the immunogenicity of PDC-E2, the major autoantigen of primary biliary cirrhosis.High incidence of glucose intolerance in Vogt-Koyanagi-Harada diseaseAutoimmune diabetes: ongoing development of immunological intervention strategies targeted directly against autoreactive T cellsAntigen-specific therapeutic approaches in Type 1 diabetesThe Development and Application of HLA Tetramers in the Detection, Characterization and Therapy of Type 1 Diabetes Mellitus.Antigen targets of type 1 diabetes autoimmunityT-cell libraries allow simple parallel generation of multiple peptide-specific human T-cell clones.The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice.HLA-B7-restricted islet epitopes are differentially recognized in type 1 diabetic children and adults and form weak peptide-HLA complexes.B-cell cross-presentation of autologous antigen precipitates diabetes.The peptide-binding motif for the human transporter associated with antigen processingIdentification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells.Killer artificial antigen-presenting cells: a novel strategy to delete specific T cells.Polyunsaturated fatty acids and membrane organization: elucidating mechanisms to balance immunotherapy and susceptibility to infectionTranslational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes.Novel autoantigens in type 1 diabetes.Recognition of human proinsulin leader sequence by class I-restricted T-cells in HLA-A*0201 transgenic mice and in human type 1 diabetes.Oral insulin treatment suppresses virus-induced antigen-specific destruction of beta cells and prevents autoimmune diabetes in transgenic mice.Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice.Detection of GAD65 autoreactive T-cells by HLA class I tetramers in type 1 diabetic patients.Eukaryotic translation initiation factor 5A inhibition alters physiopathology and immune responses in a "humanized" transgenic mouse model of type 1 diabetes.Viruses and cytotoxic T lymphocytes in type 1 diabetes.Type 1 diabetes: etiology, immunology, and therapeutic strategies.The potential of multimer technologies in type 1 diabetes prediction strategies.Pathogenic and regulatory T cells in type 1 diabetes: losing self-control, restoring it, and how to take the temperature.T cell recognition of autoantigens in human type 1 diabetes: clinical perspectivesB cells as effectors and regulators of autoimmunity.Prevention and treatment of type 1 diabetes mellitus by the manipulation of invariant natural killer T cells.The targeting of β-cells by T lymphocytes in human type 1 diabetes: clinical perspectives.
P2860
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P2860
Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes
@ast
Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes
@en
type
label
Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes
@ast
Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes
@en
prefLabel
Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes
@ast
Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes
@en
P2093
P2860
P356
P1476
Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes
@en
P2093
F Sinigaglia
G A Spinas
P Panina-Bordignon
R M Pastore
P2860
P304
P356
10.1084/JEM.181.5.1923
P407
P577
1995-05-01T00:00:00Z