about
The Alzheimer's amyloid-degrading peptidase, neprilysin: can we control it?A familial mutation renders atrial natriuretic Peptide resistant to proteolytic degradationInsulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivoZinc and Manduca sexta hemocyte functionsRare Variants in MME, Encoding Metalloprotease Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal PolyneuropathiesMolecular identification and characterization of novel membrane-bound metalloprotease, the soluble secreted form of which hydrolyzes a variety of vasoactive peptidesNeonatal lethality in mice deficient in XCE, a novel member of the endothelin-converting enzyme and neutral endopeptidase familyProteolysis controls endogenous substance P levelsNew function for an old enzyme: NEP deficient mice develop late-onset obesitySynaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterationsNeprilysin deficiency protects against fat-induced insulin secretory dysfunction by maintaining calcium influx.Brain angiotensin-converting enzymes: role of angiotensin-converting enzyme 2 in processing angiotensin II in mice.Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase.The roles of streptozotocin neurotoxicity and neutral endopeptidase in murine experimental diabetic neuropathy.Expression of neutral endopeptidase activity during clinical and experimental acute lung injury.Vasopeptidase inhibitor ilepatril (AVE7688) prevents obesity- and diabetes-induced neuropathy in C57Bl/6J mice.Genetic deficiency in neprilysin or its pharmacological inhibition initiate excessive stress-induced alcohol consumption in miceNeprilysin-2 is an important β-amyloid degrading enzyme.Natriuretic peptides: their structures, receptors, physiologic functions and therapeutic applicationsNeutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance PNatriuretic peptide metabolism, clearance and degradation.Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathyEffect of Inhibition of Angiotensin-Converting Enzyme and/or Neutral Endopeptidase on Neuropathy in High-Fat-Fed C57Bl/6J Mice.Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice.Genetically altered animal models in the kallikrein-kinin system.Global brain delivery of neprilysin gene by intravascular administration of AAV vector in mice.Neutral endopeptidase modulates septic shock.Neutral endopeptidase inhibition enhances substance P mediated inflammation due to hypomagnesemiaMutations in MME cause an autosomal-recessive Charcot-Marie-Tooth disease type 2.Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer's DiseaseConcise review: neutral endopeptidase (CD10): a multifaceted environment actor in stem cells, physiological mechanisms, and cancer.Metabolism of amyloid β peptide and pathogenesis of Alzheimer's disease.Long-term neprilysin inhibition - implications for ARNIs.Green tea reduces body fat via upregulation of neprilysin.Chronically elevated plasma C-type natriuretic peptide level stimulates skeletal growth in transgenic mice.Regulatory mechanisms that modulate signalling by G-protein-coupled receptors.Neutral endopeptidase (EC 3.4.24.11) downregulates the onset of intestinal inflammation in the nematode infected mouse.Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease.Neprilysin, obesity and the metabolic syndromeDeletion of neutral endopeptidase exacerbates intestinal inflammation induced by Clostridium difficile toxin A.
P2860
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P2860
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Neutral endopeptidase modulation of septic shock.
@ast
Neutral endopeptidase modulation of septic shock.
@en
type
label
Neutral endopeptidase modulation of septic shock.
@ast
Neutral endopeptidase modulation of septic shock.
@en
prefLabel
Neutral endopeptidase modulation of septic shock.
@ast
Neutral endopeptidase modulation of septic shock.
@en
P2093
P2860
P356
P1476
Neutral endopeptidase modulation of septic shock
@en
P2093
D Zurakowski
L F Kolakowski
M C Carroll
N P Gerard
P2860
P304
P356
10.1084/JEM.181.6.2271
P407
P577
1995-06-01T00:00:00Z