A central role for the armadillo protein plakoglobin in the autoimmune disease pemphigus vulgaris.
about
Pemphigus foliaceus IgG causes dissociation of desmoglein 1-containing junctions without blocking desmoglein 1 transinteractionThe desmosomePreclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgarisPlakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling.Inhibition of Rho A activity causes pemphigus skin blistering.Pemphigus vulgaris IgG cause loss of desmoglein-mediated adhesion and keratinocyte dissociation independent of epidermal growth factor receptorPeptides Targeting the Desmoglein 3 Adhesive Interface Prevent Autoantibody-induced Acantholysis in Pemphigus.Detection of differentially expressed basal cell proteins by mass spectrometryMechanisms of Autoantibody-Induced Pathology.Desmoglein 3, via an interaction with E-cadherin, is associated with activation of SrcPlakoglobin suppresses keratinocyte motility through both cell-cell adhesion-dependent and -independent mechanisms.Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies.Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering.The desmosomal armadillo protein plakoglobin regulates prostate cancer cell adhesion and motility through vitronectin-dependent Src signalingSignaling dependent and independent mechanisms in pemphigus vulgaris blister formationDesmoglein as a target in skin disease and beyond.Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.Mechanisms of desmosome assembly and disassembly.p38MAPK inhibition prevents disease in pemphigus vulgaris mice.Recent advances in the study of the pathophysiology of pemphigus.Current and prospective understanding of clinical classification, pathomechanisms and therapy in pemphigus.Pathogenic relevance of IgG and IgM antibodies against desmoglein 3 in blister formation in pemphigus vulgarisGlandular gene expression of sinus mucosa in chronic rhinosinusitis with and without cystic fibrosis.The extent of desmoglein 3 depletion in pemphigus vulgaris is dependent on Ca(2+)-induced differentiation: a role in suprabasal epidermal skin splitting?Mechanisms of blister induction by autoantibodies.Plakoglobin is required for maintenance of the cortical actin skeleton in early Xenopus embryos and for cdc42-mediated wound healing.How does acantholysis occur in pemphigus vulgaris: a critical review.Peptide-mediated desmoglein 3 crosslinking prevents pemphigus vulgaris autoantibody-induced skin blisteringDesmoglein autoimmunity in the pathogenesis of pemphigus.Pemphigus antibody induced phosphorylation of keratinocyte proteins.Pemphigus in the XXI century: new life to an old story.The desmosome and pemphigus.Advances in pemphigus and its endemic pemphigus foliaceus (Fogo Selvagem) phenotype: a paradigm of human autoimmunity.Involvement of the apoptotic mechanism in pemphigus foliaceus autoimmune injury of the skin.Intercellular junction assembly, dynamics, and homeostasis.Desmosomes: adhesive strength and signalling in health and disease.Apoptotic pathways in pemphigus.Pemphigus autoimmunity: hypotheses and realities.Structural and functional diversity of desmosomes.Desmosomal cadherins and signaling: lessons from autoimmune disease.
P2860
Q24530223-A95AA73E-449B-405E-AF47-F654335C4FB4Q24656653-9DB02B3B-239E-407F-B56C-835CB4199118Q27311634-1B83AF85-87EB-4AB5-9017-FA2C1F7C6154Q30496901-29450262-A1ED-4E5A-96FB-7B436469901EQ33264769-B72B2722-3A3E-455E-8747-01FC3B47B64AQ33400239-1DBEA93E-2D98-45D6-8A42-D15BA2CDF8FAQ33402377-D4F02720-E5D0-407E-A857-349EC540B8F4Q33697789-67DA4413-1788-4901-8AFB-06CD84860AC0Q33740580-25EEC2B5-4644-48BD-92B8-F08464C67A40Q33769643-F1FEC107-2099-4429-96FD-B99E31CFF730Q33936505-8D7A0ECB-0129-40C5-AB7A-BAC3BEC0B139Q33997044-E4F858CA-67B1-48BA-BB2D-524E255D2BA2Q34358279-51D07F88-A47D-4639-8214-42ED58420ABCQ34364523-CB239932-4925-4A18-98E3-6B639485C771Q34506586-54705D46-C999-46C0-A286-EB496C1BA5CEQ34634515-637545F5-60C2-41FF-A71D-724DB1DE43D2Q34870969-A7177B0E-E853-4EE5-9A7A-7F16102D853FQ35020664-7EAF2B31-39CA-436D-B3A3-BF7B225654F2Q35036492-C9DB1F6C-9A68-415A-9344-7E44A50A369EQ35099761-69449F20-DFC8-4A30-BA18-EB9333D011BBQ35099765-D9B5FB6B-852D-4B7F-AA25-27024181B3EFQ35168140-45B12FF5-4837-4839-A243-E9CEE04D619EQ35219883-D4455207-AAAE-4D96-9070-1F2F738BA288Q35235788-4B914F2C-623F-490F-BF8D-034B65BD94FCQ36307954-0C7B53DD-1FE8-4896-9BD5-7927E894D5A9Q36325638-7567EDB4-B9B7-40B5-A79D-471E3272B3DEQ36507618-E4B62003-A9D9-40B8-B39F-44C2D3412D5AQ36580336-5E461127-FC4D-4BA1-B906-27E022F7B8A1Q36652501-192A7BA3-E97F-4CA5-BEE3-E0B354E238C2Q36652509-67176840-7E89-426C-9537-8E84BD5DE04CQ36668531-599D468D-0036-4236-A575-03D9B71AE268Q36700065-27E3E476-B4D1-42E2-900E-072E70CF5A51Q37246934-554E1B01-44E7-4F1F-8A4E-27D0B7AA47F0Q37278001-DB65900E-F15D-4A3D-875D-DBDC8745FE72Q37698269-DCFF747A-7561-4934-9343-FF5E551F8A79Q37772182-3AC2EBFC-FD77-48DB-B32B-43A1E4B92CE7Q37772779-C4C5669E-5B2C-4DB5-B8F7-9174D91E9DCAQ37937040-74274BBD-44F4-46A2-B19E-8429C1045386Q38160891-0C7A91D5-8E76-47EC-A05F-04CC0EAA5281Q38181538-D7179375-74D7-471F-8484-FFC34F7E2A07
P2860
A central role for the armadillo protein plakoglobin in the autoimmune disease pemphigus vulgaris.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
A central role for the armadil ...... ne disease pemphigus vulgaris.
@ast
A central role for the armadil ...... ne disease pemphigus vulgaris.
@en
type
label
A central role for the armadil ...... ne disease pemphigus vulgaris.
@ast
A central role for the armadil ...... ne disease pemphigus vulgaris.
@en
prefLabel
A central role for the armadil ...... ne disease pemphigus vulgaris.
@ast
A central role for the armadil ...... ne disease pemphigus vulgaris.
@en
P2093
P2860
P356
P1476
A central role for the armadil ...... ne disease pemphigus vulgaris.
@en
P2093
A de Bruin
C Bierkamp
R Caldelari
P2860
P304
P356
10.1083/JCB.153.4.823
P407
P577
2001-05-01T00:00:00Z