The characteristic site-specific reactivation phenotypes of HSV-1 and HSV-2 depend upon the latency-associated transcript region
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Oral shedding of herpes simplex virus type 2.Oral mucosal lesions caused by infective microorganisms. I. Viruses and bacteria.The quantity of latent viral DNA correlates with the relative rates at which herpes simplex virus types 1 and 2 cause recurrent genital herpes outbreaks.Prospects for control of herpes simplex virus disease through immunization.Prediction and identification of herpes simplex virus 1-encoded microRNAs.Spread of herpes simplex virus to the spinal cord is independent of spread to dorsal root ganglia.Herpes simplex virus 2 microRNA miR-H6 is a novel latency-associated transcript-associated microRNA, but reduction of its expression does not influence the establishment of viral latency or the recurrence phenotype.Of mice and not humans: how reliable are animal models for evaluation of herpes CD8(+)-T cell-epitopes-based immunotherapeutic vaccine candidates?Experimental investigation of herpes simplex virus latencyCharacterization of herpes simplex virus 2 primary microRNA Transcript regulationHerpes simplex virus type 2 (HSV-2) establishes latent infection in a different population of ganglionic neurons than HSV-1: role of latency-associated transcripts.Herpes simplex virus latency-associated transcript sequence downstream of the promoter influences type-specific reactivation and viral neurotropism.A viral function represses accumulation of transcripts from productive-cycle genes in mouse ganglia latently infected with herpes simplex virus.A LAT-associated function reduces productive-cycle gene expression during acute infection of murine sensory neurons with herpes simplex virus type 1.HSV-1 latent rabbits shed viral DNA into their saliva.An acutely and latently expressed herpes simplex virus 2 viral microRNA inhibits expression of ICP34.5, a viral neurovirulence factor.Assessing the efficacy of cidofovir against herpesvirus-induced genital lesions in goats using different therapeutic regimens.Role of immediate early protein ICP27 in the differential sensitivity of herpes simplex viruses 1 and 2 to leptomycin BOcular HSV-1 latency, reactivation and recurrent disease.Investigation of the mechanism by which herpes simplex virus type 1 LAT sequences modulate preferential establishment of latent infection in mouse trigeminal ganglia.Novel less-abundant viral microRNAs encoded by herpes simplex virus 2 latency-associated transcript and their roles in regulating ICP34.5 and ICP0 mRNAs.Latency-associated transcript (LAT) exon 1 controls herpes simplex virus species-specific phenotypes: reactivation in the guinea pig genital model and neuron subtype-specific latent expression of LATWorldwide circulation of HSV-2 × HSV-1 recombinant strains.Comparison of clinical manifestations, outcomes and cerebrospinal fluid findings between herpes simplex type 1 and type 2 central nervous system infections in adults.A protein encoded by the herpes simplex virus (HSV) type 1 2-kilobase latency-associated transcript is phosphorylated, localized to the nucleus, and overcomes the repression of expression from exogenous promoters when inserted into the quiescent HSVDifferent mechanisms regulate productive herpes simplex virus 1 (HSV-1) and HSV-2 infections in adult trigeminal neurons.Herpes simplex virus type-1 latency-associated transcript-induced immunoreactivity of substance P in trigeminal neurons is reversed by bone morphogenetic protein-7.An HSV-1 chimeric containing HSV-2 latency associated transcript (LAT) sequences has significantly reduced adrenergic reactivation in the rabbit eye model.Herpes Simplex Virus 2 Latency-Associated Transcript (LAT) region mutations do not identify a role for LAT-Associated Micro RNAs in viral reactivation in the Guinea Pig Genital Model.Chester Chronicles: Paddy.
P2860
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P2860
The characteristic site-specific reactivation phenotypes of HSV-1 and HSV-2 depend upon the latency-associated transcript region
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
The characteristic site-specif ...... y-associated transcript region
@ast
The characteristic site-specif ...... y-associated transcript region
@en
type
label
The characteristic site-specif ...... y-associated transcript region
@ast
The characteristic site-specif ...... y-associated transcript region
@en
prefLabel
The characteristic site-specif ...... y-associated transcript region
@ast
The characteristic site-specif ...... y-associated transcript region
@en
P2093
P2860
P356
P1476
The characteristic site-specif ...... y-associated transcript region
@en
P2093
J F Kurawadwala
L R Stanberry
T Yoshikawa
P2860
P304
P356
10.1084/JEM.184.2.659
P407
P577
1996-08-01T00:00:00Z