Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB. - Wikidata - awgldk - TriplyDB

Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB.

Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB.

http://www.wikidata.org/entity/Q36377290

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Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105 Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors 3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling IkappaBalpha and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFkappaB pathways NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis NF-kB inhibitor blocks B cell development at two checkpoints Transplantation tolerance and its outcome during infections and inflammation Role of T cell-nuclear factor κB in transplantation To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis Murine Schnurri-2 is required for positive selection of thymocytes Double-stranded RNA-activated protein kinase regulates early innate immune responses during respiratory syncytial virus infection POLKADOTS are foci of functional interactions in T-Cell receptor-mediated signaling to NF-kappaB.Expression of Mad1 in T cells leads to reduced thymic cellularity and impaired mitogen-induced proliferation Complex and dynamic redistribution of NF-kappaB signaling intermediates in response to T cell receptor stimulation Basal NF-κB controls IL-7 responsiveness of quiescent naïve T cells Distinct domains of IkappaBalpha regulate c-Rel in the cytoplasm and in the nucleus.Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts.Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases.Roles of the NF-kappaB pathway in lymphocyte development and function.Premalignant PTEN-deficient thymocytes activate microRNAs miR-146a and miR-146b as a cellular defense against malignant transformation.CARMA1 regulation of regulatory T cell development involves modulation of interleukin-2 receptor signaling.Regulation of natural killer T-cell development by deubiquitinase CYLD Cell-intrinsic NF-κB activation is critical for the development of natural regulatory T cells in mice.Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny Inhibition of NF-kappaB signaling reduces virus load and gammaherpesvirus-induced pulmonary fibrosis Genetic evidence for Shc requirement in TCR-induced c-Rel nuclear translocation and IL-2 expression.Tenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection.Role of NF-kappa B in T-lymphocyte development.Increased p300 expression inhibits glucocorticoid receptor-T-cell receptor antagonism but does not affect thymocyte positive selection Role of interleukin-7 in T-cell development from hematopoietic stem cells.The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression.NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions.IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival.T cell-NF-κB activation is required for tumor control in vivo Kinetic perspectives of T cell antigen receptor signaling. A two-tier model for T cell full activation.NF-kappaB regulation of endothelial cell function during LPS-induced toxemia and cancer.Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice.Requirement for NF-kappaB in osteoclast and B-cell development A novel mutation in NFKBIA/IKBA results in a degradation-resistant N-truncated protein and is associated with ectodermal dysplasia with immunodeficiency.Transgenic expression of the coxsackie/adenovirus receptor enables adenoviral-mediated gene delivery in naive T cells.

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P2860

Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB.

http://www.wikidata.org/entity/Q36377290

description

1997 nî lūn-bûn

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1997年の論文

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年学术文章

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1997年學術文章

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1997年學術文章

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1997年學術文章

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name

Perturbation of the T lymphocy ...... of nuclear factor (NF)-kappaB.

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Perturbation of the T lymphocy ...... of nuclear factor (NF)-kappaB.

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type

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Perturbation of the T lymphocy ...... of nuclear factor (NF)-kappaB.

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Perturbation of the T lymphocy ...... of nuclear factor (NF)-kappaB.

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prefLabel

Perturbation of the T lymphocy ...... of nuclear factor (NF)-kappaB.

@ast

Perturbation of the T lymphocy ...... of nuclear factor (NF)-kappaB.

@en

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JEM.185.11.1897

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Journal of Experimental Medicine

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Perturbation of the T lymphocy ...... of nuclear factor (NF)-kappaB.

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A L Mora

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D C Scherer

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D W Ballard

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J A Brockman

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M R Boothby

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P2860

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency

IL-4 induces IL-2 receptor p75 beta-chain gene expression and IL-2-dependent proliferation in mouse T lymphocytes

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment

Expression of relB is required for the development of thymic medulla and dendritic cells

Function and activation of NF-kappa B in the immune system

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1897-1907

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9166419

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2196335

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