Significance of Lyt phenotypes: Lyt2 antibodies block activities of T cells that recognize class 1 major histocompatibility complex antigens regardless of their function.
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The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibodyActivation of human T lymphocytes: differential effects of CD3- and CD8-mediated signals.Coaggregation of the T-cell receptor with CD4 and other T-cell surface molecules enhances T-cell activation.In vitro Studies of the Antibody Response: Antibodies of Different Specificity are Made in Different Populations of CellsMolecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions.Generation of gamma interferon responses in murine Peyer's patches following oral immunization.Phenotypic and functional characterization of human cytolytic T cells lacking expression of CD5.Requirement for CD8-major histocompatibility complex class I interaction in positive and negative selection of developing T cells.Long-term human cytolytic T-cell lines allospecific for HLA-DR6 antigen are OKT4+.Clonal analysis of human cytotoxic T lymphocytes: T4+ and T8+ effector T cells recognize products of different major histocompatibility complex regions.Possible involvement of the OKT4 molecule in T cell recognition of class II HLA antigens. Evidence from studies of cytotoxic T lymphocytes specific for SB antigens.Precursor frequency analysis of lymphokine-secreting alloreactive T lymphocytes. Dissociation of subsets producing interleukin 2, macrophage-activating factor, and granulocyte-macrophage colony-stimulating factor on the basis of Lyt-2 phenotypeInduction of Ia antigen in rat epidermal cells and gut epithelium by immunological stimuli.Spontaneous release of the Leu-2 (T8) molecule from human T cellsT cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4.Possible involvement of the T4 molecule in T cell recognition of class II HLA antigens. Evidence from studies of CTL-target cell bindingThe role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma.Absence of the Lyt-2-,L3T4+ lineage of T cells in mice treated neonatally with anti-I-A correlates with absence of intrathymic I-A-bearing antigen-presenting cell function.Role of L3T4 in antigen-driven activation of a class I-specific T cell hybridoma.Cloned cytotoxic T lymphocytes that recognize an I-A region product in the context of a class I antigen.A single amino acid substitution in the alpha 3 domain of an H-2 class I molecule abrogates reactivity with CTL.Characterization of Lyt-2-, L3T4- class I-specific cytolytic clones in C3H-gld/gld mice. Implications for functions of accessory molecules and programmed development.Expression and function of CD8 in a murine T cell hybridoma.The Lyt-2 molecule recognizes residues in the class I alpha 3 domain in allogeneic cytotoxic T cell responses.Functional consequences of anti-sense RNA-mediated inhibition of CD8 surface expression in a human T cell clone.Toxicity and therapeutic efficacy of high-dose interleukin 2. In vivo infusion of antibody to NK-1.1 attenuates toxicity without compromising efficacy against murine leukemiaDirect evidence for binding of CD8 to HLA class I antigens.B cell stimulatory factor 1 (interleukin 4) is sufficient for the proliferation and differentiation of lectin-stimulated cytolytic T lymphocyte precursors.Hybrid antibody mediated veto of cytotoxic T lymphocyte responses.Mechanism of recovery from acute virus infection: treatment of lymphocytic choriomeningitis virus-infected mice with monoclonal antibodies reveals that Lyt-2+ T lymphocytes mediate clearance of virus and regulate the antiviral antibody response.Interstitial murine cytomegalovirus pneumonia after irradiation: characterization of cells that limit viral replication during established infection of the lungs.A synaptic basis for T-lymphocyte activation.Modification of acute murine cytomegalovirus adrenal gland infection by adoptive spleen cell transferImmunoregulation of genetically controlled acquired responses to Leishmania donovani infection in mice: demonstration and characterization of suppressor T cells in noncure mice.Expression of T-cell-activating protein in peripheral lymphocyte subsets.CD8+ T cells (cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites.Xenogeneic antiserum to soluble products from activated lymphoid cells inhibits interleukin 1-mediated functions in the helper pathway of cytolytic-effector-cell differentiation.Vasoactive intestinal peptide as a modulator of lymphocyte and immune function.Functional analysis of CD2, CD4, and CD8 in T-cell activation.The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product.
P2860
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P2860
Significance of Lyt phenotypes: Lyt2 antibodies block activities of T cells that recognize class 1 major histocompatibility complex antigens regardless of their function.
description
1981 nî lūn-bûn
@nan
1981年の論文
@ja
1981年学术文章
@wuu
1981年学术文章
@zh-cn
1981年学术文章
@zh-hans
1981年学术文章
@zh-my
1981年学术文章
@zh-sg
1981年學術文章
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1981年學術文章
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1981年學術文章
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name
Significance of Lyt phenotypes ...... regardless of their function.
@ast
Significance of Lyt phenotypes ...... regardless of their function.
@en
type
label
Significance of Lyt phenotypes ...... regardless of their function.
@ast
Significance of Lyt phenotypes ...... regardless of their function.
@en
prefLabel
Significance of Lyt phenotypes ...... regardless of their function.
@ast
Significance of Lyt phenotypes ...... regardless of their function.
@en
P2860
P356
P1476
Significance of Lyt phenotypes ...... regardless of their function.
@en
P2093
P2860
P304
P356
10.1073/PNAS.78.11.7101
P407
P577
1981-11-01T00:00:00Z