Murine gammaherpesvirus M2 gene is latency-associated and its protein a target for CD8(+) T lymphocytes.
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Gamma-herpesvirus latency requires T cell evasion during episome maintenanceDefining immune engagement thresholds for in vivo control of virus-driven lymphoproliferationMurid herpesvirus-4 exploits dendritic cells to infect B cellsNatural history of murine -herpesvirus infectionEffective control of chronic gamma-herpesvirus infection by unconventional MHC Class Ia-independent CD8 T cells.Murine gammaherpesvirus-68 inhibits antigen presentation by dendritic cellsThe Gammaherpesvirus m2 protein manipulates the Fyn/Vav pathway through a multidocking mechanism of assemblyIdentification of closely spaced but distinct transcription initiation sites for the murine gammaherpesvirus 68 latency-associated M2 gene.Endothelial cells support persistent gammaherpesvirus 68 infection.A single CD8+ T cell epitope sets the long-term latent load of a murid herpesvirusRTA promoter demethylation and histone acetylation regulation of murine gammaherpesvirus 68 reactivationAn in vitro system for studying murid herpesvirus-4 latency and reactivation.Induction of protective immunity against murine gammaherpesvirus 68 infection in the absence of viral latency.Differential impact of ageing on cellular and humoral immunity to a persistent murine gamma-herpesvirusPathogenesis of a model gammaherpesvirus in a natural hostDissecting the host response to a gamma-herpesvirus.The murine gammaherpesvirus 68 M2 gene is required for efficient reactivation from latently infected B cells.Disruption of the murine gammaherpesvirus 68 M1 open reading frame leads to enhanced reactivation from latency.Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency.T-cell vaccination alters the course of murine herpesvirus 68 infection and the establishment of viral latency in mice.Regression of a murine gammaherpesvirus 68-positive b-cell lymphoma mediated by CD4 T lymphocytes.Kinetics of murine gammaherpesvirus 68 gene expression following infection of murine cells in culture and in mice.An Epstein-Barr virus isolated from a lymphoblastoid cell line has a 16-kilobase-pair deletion which includes gp350 and the Epstein-Barr virus nuclear antigen 3ACharacterization of a novel wood mouse virus related to murid herpesvirus 4.Dendritic cells loaded with tumor B cells elicit broad immunity against murine gammaherpesvirus 68 but fail to prevent long-term latencyEvolutionary aspects of oncogenic herpesvirusesDisruption of the M2 gene of murine gammaherpesvirus 68 alters splenic latency following intranasal, but not intraperitoneal, inoculation.Gammaherpesvirus lytic gene expression as characterized by DNA array.Characterization of a spontaneous 9.5-kilobase-deletion mutant of murine gammaherpesvirus 68 reveals tissue-specific genetic requirements for latency.Epstein-Barr virus IL-10 gene expression by a recombinant murine gammaherpesvirus in vivo enhances acute pathogenicity but does not affect latency or reactivation.Unbiased mutagenesis of MHV68 LANA reveals a DNA-binding domain required for LANA function in vitro and in vivo.Glycogen Synthase Kinase 3 Inactivation Drives T-bet-Mediated Downregulation of Co-receptor PD-1 to Enhance CD8(+) Cytolytic T Cell Responses.Persistent gamma-herpesvirus infections: what can we learn from an experimental mouse model?Activation of Vav by the gammaherpesvirus M2 protein contributes to the establishment of viral latency in B lymphocytesChemokine binding protein M3 of murine gammaherpesvirus 68 modulates the host response to infection in a natural hostGammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protectionSelective gene expression of latent murine gammaherpesvirus 68 in B lymphocytes.Different functional capacities of latent and lytic antigen-specific CD8 T cells in murine gammaherpesvirus infection.Tiled microarray identification of novel viral transcript structures and distinct transcriptional profiles during two modes of productive murine gammaherpesvirus 68 infection.Murine gammaherpesvirus 68 LANA acts on terminal repeat DNA to mediate episome persistence.
P2860
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P2860
Murine gammaherpesvirus M2 gene is latency-associated and its protein a target for CD8(+) T lymphocytes.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Murine gammaherpesvirus M2 gen ...... rget for CD8(+) T lymphocytes.
@ast
Murine gammaherpesvirus M2 gen ...... rget for CD8(+) T lymphocytes.
@en
type
label
Murine gammaherpesvirus M2 gen ...... rget for CD8(+) T lymphocytes.
@ast
Murine gammaherpesvirus M2 gen ...... rget for CD8(+) T lymphocytes.
@en
prefLabel
Murine gammaherpesvirus M2 gen ...... rget for CD8(+) T lymphocytes.
@ast
Murine gammaherpesvirus M2 gen ...... rget for CD8(+) T lymphocytes.
@en
P2093
P2860
P356
P1476
Murine gammaherpesvirus M2 gen ...... arget for CD8(+) T lymphocytes
@en
P2093
C Coleclough
D L Woodland
E J Usherwood
J T Sample
M A Blackman
M A Coppola
S M Husain
P2860
P304
P356
10.1073/PNAS.96.13.7508
P407
P577
1999-06-01T00:00:00Z