Viral and bacterial infections interfere with peripheral tolerance induction and activate CD8+ T cells to cause immunopathology
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Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic miceOn the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease.Role of dendritic cells in the induction and maintenance of autoimmune diseases.Peripheral T-cell tolerance: the contribution of permissive T-cell migration into parenchymal tissues of the neonate.Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to beta cell damageGlycoprotein 96 can chaperone both MHC class I- and class II-restricted epitopes for in vivo presentation, but selectively primes CD8+ T cell effector function.Virus-induced abrogation of transplantation tolerance induced by donor-specific transfusion and anti-CD154 antibody.Occult cytomegalovirus in vivarium-housed mice may influence transplant allograft acceptance.Peripheral T-cell tolerance defined through transgenic mouse studies.Microchimerism maintains deletion of the donor cell-specific CD8+ T cell repertoireSignal 3 cytokines as modulators of primary immune responses during infections: the interplay of type I IFN and IL-12 in CD8 T cell responses.Liver restores immune homeostasis after local inflammation despite the presence of autoreactive T cells.The enemy within: keeping self-reactive T cells at bay in the periphery.CD154 is a negative regulator of autoaggressive CD8+ T cells in type 1 diabetesCynomolgus polyoma virus infection: a new member of the polyoma virus family causes interstitial nephritis, ureteritis, and enteritis in immunosuppressed cynomolgus monkeysRelative importance of T-cell subsets in monocytotropic ehrlichiosis: a novel effector mechanism involved in Ehrlichia-induced immunopathology in murine ehrlichiosis.Immunologic ignorance of vascular endothelial cells expressing minor histocompatibility antigenThe role of bystander T cells in CNS pathology and pathogen clearance.The effect of graft-versus-host disease on T cell production and homeostasis.Influenza virus lung infection protects from respiratory syncytial virus-induced immunopathology.Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompNeonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells.Immunotherapy with dendritic cells directed against tumor antigens shared with normal host cells results in severe autoimmune disease.Phenotypic and functional analysis of CD8(+) T cells undergoing peripheral deletion in response to cross-presentation of self-antigen.Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue.Role of antigen-presenting cells in mediating tolerance and autoimmunity.Ontogeny of T cell tolerance to peripherally expressed antigens.Time, space and contextual models of the immunity tolerance decision: bridging the geographical divide of Zinkernagel and Hengartner's 'Credo 2004'.Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ.Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD miceImmunoregulatory dendritic cells to prevent and reverse new-onset Type 1 diabetes mellitus.Disruption of murine cardiac allograft acceptance by latent cytomegalovirus.Phenotypic differences between healthy effector CTL and leukemic LGL cells support the notion of antigen-triggered clonal transformation in T-LGL leukemia.Too dangerous to ignore: self-tolerance and the control of ignorant autoreactive T cells.HMGB1, an innate alarmin, in the pathogenesis of type 1 diabetes.Rebuilding an immune-mediated central nervous system disease: weighing the pathogenicity of antigen-specific versus bystander T cells.Dendritic cell-based therapy in Type 1 diabetes mellitus.Co-inhibitory molecules: Controlling the effectors or controlling the controllers?CTL induction by cross-priming is restricted to immunodominant epitopes.Inflammation promotes the loss of adeno-associated virus-mediated transgene expression in mouse liver.
P2860
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P2860
Viral and bacterial infections interfere with peripheral tolerance induction and activate CD8+ T cells to cause immunopathology
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Viral and bacterial infections ...... cells to cause immunopathology
@ast
Viral and bacterial infections ...... cells to cause immunopathology
@en
type
label
Viral and bacterial infections ...... cells to cause immunopathology
@ast
Viral and bacterial infections ...... cells to cause immunopathology
@en
prefLabel
Viral and bacterial infections ...... cells to cause immunopathology
@ast
Viral and bacterial infections ...... cells to cause immunopathology
@en
P2093
P2860
P356
P1476
Viral and bacterial infections ...... cells to cause immunopathology
@en
P2093
Hengartner H
Odermatt B
Zinkernagel R
P2860
P304
P356
10.1084/JEM.187.5.763
P407
P577
1998-03-01T00:00:00Z