Regulation of cloned ATP-sensitive K channels by phosphorylation, MgADP, and phosphatidylinositol bisphosphate (PIP(2)): a study of channel rundown and reactivation
about
Running out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channelsProtection of cardiac mitochondria by diazoxide and protein kinase C: implications for ischemic preconditioning.Molecular basis for Kir6.2 channel inhibition by adenine nucleotides.ATP-sensitive potassium channels exhibit variance in the number of open channels below the limit predicted for identical and independent gatingStabilization of the activity of ATP-sensitive potassium channels by ion pairs formed between adjacent Kir6.2 subunits.Hydrolyzable ATP and PIP(2) modulate the small-conductance K+ channel in apical membranes of rat cortical-collecting duct (CCD).Regulation of cloned ATP-sensitive K channels by adenine nucleotides and sulfonylureas: interactions between SUR1 and positively charged domains on Kir6.2.Role for SUR2A ED domain in allosteric coupling within the K(ATP) channel complex.Ligand-dependent linkage of the ATP site to inhibition gate closure in the KATP channelRegulation of ABC transporter function via phosphorylation by protein kinases.Incomplete dissociation of glibenclamide from wild-type and mutant pancreatic K ATP channels limits their recovery from inhibition.ATP-sensitive K+ channels: regulation of bursting by the sulphonylurea receptor, PIP2 and regions of Kir6.2.ATP sensitivity of ATP-sensitive K+ channels: role of the gamma phosphate group of ATP and the R50 residue of mouse Kir6.2.Interaction of a novel dihydropyridine K+ channel opener, A-312110, with recombinant sulphonylurea receptors and KATP channels: comparison with the cyanoguanidine P1075.Phosphorylation-dependent changes in nucleotide binding, conformation, and dynamics of the first nucleotide binding domain (NBD1) of the sulfonylurea receptor 2B (SUR2B).Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: a mechanistic studyControl of Kir channel gating by cytoplasmic domain interface interactionsPhosphatidic acid stimulates cardiac KATP channels like phosphatidylinositols, but with novel gating kinetics.Compromised ATP binding as a mechanism of phosphoinositide modulation of ATP-sensitive K+ channels.Phosphatidylinositol 4,5-bisphosphate (PIP2) modulation of ATP and pH sensitivity in Kir channels. A tale of an active and a silent PIP2 site in the N terminus.A mutation in the ATP-binding site of the Kir6.2 subunit of the KATP channel alters coupling with the SUR2A subunit.Involvement of the phosphatidylinositol kinase pathway in augmentation of ATP-sensitive K(+) channel currents by hypo-osmotic stress in rat ventricular myocytes.Lipid signaling to membrane proteins: From second messengers to membrane domains and adapter-free endocytosis.Cryo-electron microscopy structures and progress toward a dynamic understanding of KATP channels.
P2860
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P2860
Regulation of cloned ATP-sensitive K channels by phosphorylation, MgADP, and phosphatidylinositol bisphosphate (PIP(2)): a study of channel rundown and reactivation
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
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name
Regulation of cloned ATP-sensi ...... annel rundown and reactivation
@ast
Regulation of cloned ATP-sensi ...... annel rundown and reactivation
@en
type
label
Regulation of cloned ATP-sensi ...... annel rundown and reactivation
@ast
Regulation of cloned ATP-sensi ...... annel rundown and reactivation
@en
prefLabel
Regulation of cloned ATP-sensi ...... annel rundown and reactivation
@ast
Regulation of cloned ATP-sensi ...... annel rundown and reactivation
@en
P2093
P2860
P356
P1476
Regulation of cloned ATP-sensi ...... annel rundown and reactivation
@en
P2093
P2860
P304
P356
10.1085/JGP.116.3.391
P577
2000-09-01T00:00:00Z