Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein - Wikidata - awgldk - TriplyDB

Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein

Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein

http://www.wikidata.org/entity/Q36490601

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Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells Identification of a novel Skp2-like mammalian protein containing F-box and leucine-rich repeats APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex TIP120A associates with cullins and modulates ubiquitin ligase activity The Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for normal mitosis in mammalian cells Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2 SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2 The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U Conjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to von Hippel-Lindau tumor suppressor function The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p.Analysis of CUL-5 expression in breast epithelial cells, breast cancer cell lines, normal tissues and tumor tissues Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels.The role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implications A novel mutation in β integrin reveals an integrin-mediated interaction between the extracellular matrix and cki-1/p27KIP1 The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression.The unstable F-box protein p58-Ctf13 forms the structural core of the CBF3 kinetochore complex SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis.Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes Identification of determinants in E2 ubiquitin-conjugating enzymes required for hect E3 ubiquitin-protein ligase interaction Covalent modification of all members of human cullin family proteins by NEDD8 Phosphorylation of Ser72 is dispensable for Skp2 assembly into an active SCF ubiquitin ligase and its subcellular localization Characterization of the cullin and F-box protein partner Skp1 Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle CUL-4A is critical for early embryonic development Diversification of the cullin family.Regulation of the G1 to S transition by the ubiquitin pathway.The UNUSUAL FLORAL ORGANS gene of Arabidopsis thaliana is an F-box protein required for normal patterning and growth in the floral meristem.Analysis of newly established EST databases reveals similarities between heart regeneration in newt and fish.Inactivation of the cyclin-dependent kinase inhibitor p27 upon loss of the tuberous sclerosis complex gene-2 Two distinct ubiquitin-proteolysis pathways in the fission yeast cell cycle Hsp90-Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites.SKP1-SnRK protein kinase interactions mediate proteasomal binding of a plant SCF ubiquitin ligase.Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

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Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein

http://www.wikidata.org/entity/Q36490601

description

1998 nî lūn-bûn

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1998年の論文

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

@zh-sg

1998年學術文章

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1998年學術文章

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1998年學術文章

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name

Human CUL1 forms an evolutiona ...... with SKP1 and an F-box protein

@ast

Human CUL1 forms an evolutiona ...... with SKP1 and an F-box protein

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type

label

Human CUL1 forms an evolutiona ...... with SKP1 and an F-box protein

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Human CUL1 forms an evolutiona ...... with SKP1 and an F-box protein

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prefLabel

Human CUL1 forms an evolutiona ...... with SKP1 and an F-box protein

@ast

Human CUL1 forms an evolutiona ...... with SKP1 and an F-box protein

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PNAS.95.13.7451

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Human CUL1 forms an evolutiona ...... with SKP1 and an F-box protein

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P2093

C C Correll

http://www.w3.org/2001/XMLSchema#string

E T Kipreos

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R J Deshaies

http://www.w3.org/2001/XMLSchema#string

S A Lyapina

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P2860

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeast

Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E

The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

High-efficiency transformation of mammalian cells by plasmid DNA

A novel genetic system to detect protein-protein interactions

Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression.

Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex.

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7451-7456

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10.1073/PNAS.95.13.7451

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13

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13648800

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9636170

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22647

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