Critical involvement of pneumolysin in production of interleukin-1alpha and caspase-1-dependent cytokines in infection with Streptococcus pneumoniae in vitro: a novel function of pneumolysin in caspase-1 activation
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Inflammasome/IL-1β Responses to Streptococcal PathogensRole of Toll-like receptors 2 and 4 in pulmonary inflammation and injury induced by pneumolysin in mice.Streptococcus pneumoniae synergizes with nontypeable Haemophilus influenzae to induce inflammation via upregulating TLR2Type I interferon signaling regulates activation of the absent in melanoma 2 inflammasome during Streptococcus pneumoniae infection.Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.Streptococcus pyogenes cytolysin-mediated translocation does not require pore formation by streptolysin O.TLR-mediated inflammatory responses to Streptococcus pneumoniae are highly dependent on surface expression of bacterial lipoproteinsCaspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization.Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice.Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection.Peptidoglycan Branched Stem Peptides Contribute to Streptococcus pneumoniae Virulence by Inhibiting Pneumolysin Release.Inflammatory monocytes activate memory CD8(+) T and innate NK lymphocytes independent of cognate antigen during microbial pathogen invasionNonpathogenic Lactobacillus rhamnosus activates the inflammasome and antiviral responses in human macrophages.Streptococcus pneumoniae Endopeptidase O (PepO) Elicits a Strong Innate Immune Response in Mice via TLR2 and TLR4 Signaling Pathways.Role of oxidative stress in the pathophysiology of pneumococcal meningitis.Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent mannerMucosal immunization with recombinant fusion protein DnaJ-ΔA146Ply enhances cross-protective immunity against Streptococcus pneumoniae infection in mice via interleukin 17A.Pneumococci: immunology of the innate host response.Recognition of Streptococcus pneumoniae by the innate immune system.Licensing Adaptive Immunity by NOD-Like Receptors.Streptococcus pneumoniae induces pyroptosis through the regulation of autophagy in murine microglia.Inflammasomes in Pneumococcal Infection: Innate Immune Sensing and Bacterial Evasion Strategies.Detoxified pneumolysin derivative Plym2 directly protects against pneumococcal infection via induction of inflammatory cytokines.Toll-Like Receptor 3/TRIF-Dependent IL-12p70 Secretion Mediated by Streptococcus pneumoniae RNA and Its Priming by Influenza A Virus Coinfection in Human Dendritic Cells.Pneumolysin-Dependent Calpain Activation and Interleukin-1α Secretion in Macrophages Infected with Streptococcus pneumoniae.Caspase-11 protects against bacteria that escape the vacuole.Streptococcus pneumoniae evades human dendritic cell surveillance by pneumolysin expression.How inflammasomes inform adaptive immunity.The diversity of receptor recognition in cholesterol-dependent cytolysins.NLRP3 Inflammasome Activation in Aged Macrophages is diminished during Streptococcus pneumoniae Infection.Decreased NLRP3 inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection.GHIP in Streptococcus pneumoniae is involved in antibacterial resistance and elicits a strong innate immune response through TLR2 and JNK/p38MAPK.Induction ofManduca sextaLarvae Caspases Expression in Midgut Cells byBacillus thuringiensisCry1Ab ToxinDefense and death responses to pore forming toxinsAge-related differences in IL-1 signaling and capsule serotype affect persistence of Streptococcus pneumoniae colonization
P2860
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P2860
Critical involvement of pneumolysin in production of interleukin-1alpha and caspase-1-dependent cytokines in infection with Streptococcus pneumoniae in vitro: a novel function of pneumolysin in caspase-1 activation
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Critical involvement of pneumo ...... olysin in caspase-1 activation
@ast
Critical involvement of pneumo ...... olysin in caspase-1 activation
@en
type
label
Critical involvement of pneumo ...... olysin in caspase-1 activation
@ast
Critical involvement of pneumo ...... olysin in caspase-1 activation
@en
prefLabel
Critical involvement of pneumo ...... olysin in caspase-1 activation
@ast
Critical involvement of pneumo ...... olysin in caspase-1 activation
@en
P2093
P2860
P356
P1476
Critical involvement of pneumo ...... olysin in caspase-1 activation
@en
P2093
Hideki Hara
Ikuo Kawamura
Masao Mitsuyama
Ryosuke Uchiyama
Shereen Shoma
Sylvia Daim
Takamasa Nomura
P2860
P304
P356
10.1128/IAI.01269-07
P407
P577
2008-01-14T00:00:00Z