A functional T-cell receptor signaling pathway is required for p95vav activity.
about
hSiah2 is a new Vav binding protein which inhibits Vav-mediated signaling pathwaysSLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activityFunctional association between SLAP-130 and SLP-76 in Jurkat T cellsFunctional cloning of Src-like adapter protein-2 (SLAP-2), a novel inhibitor of antigen receptor signalingDiscs large (Dlg1) complexes in lymphocyte activationPhosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1CImmunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cellsIQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42HsVav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation.Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFATVav family proteins couple to diverse cell surface receptorsRegulatory and signaling properties of the Vav familyVav-2 controls NFAT-dependent transcription in B- but not T-lymphocytesImplication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 productionRasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responsesSignalling pathways induced by protease-activated receptors and integrins in T cellsVav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancerVav family exchange factors: an integrated regulatory and functional viewTwo Closely Spaced Tyrosines Regulate NFAT Signaling in B Cells via Syk Association with VavVav, a GDP/GTP nucleotide exchange factor, interacts with GDIs, proteins that inhibit GDP/GTP dissociationVav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyteVav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathwaysCytohesin binder and regulator augments T cell receptor-induced nuclear factor of activated T Cells.AP-1 activation through regulation of the JNK pathwaySos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptorsDifferential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphataseTyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcriptionFyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cellsThe C-terminal SH3 domain contributes to the intramolecular inhibition of Vav family proteins.Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity.An active form of Vav1 induces migration of mammary epithelial cells by stimulating secretion of an epidermal growth factor receptor ligandMembrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76.T cell receptor-induced activation of phospholipase C-gamma1 depends on a sequence-independent function of the P-I region of SLP-76.Structural determinants for the biological activity of Vav proteins.Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signalingp95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cellsVav: function and regulation in hematopoietic cell signaling.A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNKInterdomain B in ZAP-70 regulates but is not required for ZAP-70 signaling function in lymphocytes.Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoterVav1 regulates phospholipase cgamma activation and calcium responses in mast cells.
P2860
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P2860
A functional T-cell receptor signaling pathway is required for p95vav activity.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
A functional T-cell receptor signaling pathway is required for p95vav activity.
@ast
A functional T-cell receptor signaling pathway is required for p95vav activity.
@en
type
label
A functional T-cell receptor signaling pathway is required for p95vav activity.
@ast
A functional T-cell receptor signaling pathway is required for p95vav activity.
@en
prefLabel
A functional T-cell receptor signaling pathway is required for p95vav activity.
@ast
A functional T-cell receptor signaling pathway is required for p95vav activity.
@en
P2093
P2860
P356
P1476
A functional T-cell receptor signaling pathway is required for p95vav activity.
@en
P2093
P2860
P304
P356
10.1128/MCB.15.8.4337
P407
P577
1995-08-01T00:00:00Z