Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase.
about
Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro.Minimum length requirement of the alignment domain of human telomerase RNA to sustain catalytic activity in vitroPolymerization defects within human telomerase are distinct from telomerase RNA and TEP1 bindingRNA-dependent activation of primer RNA production by influenza virus polymerase: different regions of the same protein subunit constitute the two required RNA-binding sites.SnoRNA-guided ribose methylation of rRNA: structural features of the guide RNA duplex influencing the extent of the reactionYeast telomerase is specialized for C/A-rich RNA templates.The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesisTelomeres and telomerase.Human telomerase RNA template sequence is a determinant of telomere repeat extension rate.De novo telomere addition by Tetrahymena telomerase in vitro.Developmentally regulated initiation of DNA synthesis by telomerase: evidence for factor-assisted de novo telomere formation.Telomerase can act as a template- and RNA-independent terminal transferase.Expression of mutated Paramecium telomerase RNAs in vivo leads to templating errors that resemble those made by retroviral reverse transcriptase.Molecular basis for telomere repeat divergence in budding yeastTelomerase recognizes its template by using an adjacent RNA motif.Characterization of terminal deletions at 7q32 and 22q13.3 healed by De novo telomere additionTelomere maintenance mechanisms as a target for drug development.Studies on the minimal lengths required for DNA primers to be extended by the Tetrahymena telomerase: implications for primer positioning by the enzyme.Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility.Telomerase as a therapeutic target for malignant gliomas.Mutational analysis of the Tetrahymena telomerase RNA: identification of residues affecting telomerase activity in vitroReiterative dG addition by Euplotes crassus telomerase during extension of non-telomeric DNA.Interaction of recombinant Tetrahymena telomerase proteins p80 and p95 with telomerase RNA and telomeric DNA substrates.Specific telomerase RNA residues distant from the template are essential for telomerase function.High-resolution physical and functional mapping of the template adjacent DNA binding site in catalytically active telomerase.Adding to the ends: what makes telomerase processive and how important is it?A novel pseudoknot element is essential for the action of a yeast telomerase.A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domainsEffects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines.A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase proteinTelomerase: an RNP enzyme synthesizes DNA.Interference footprinting analysis of telomerase elongation complexes.Tracing the path of DNA substrates in active Tetrahymena telomerase holoenzyme complexes: mapping of DNA contact sites in the RNA subunitIdentification of Kluyveromyces lactis telomerase: discontinuous synthesis along the 30-nucleotide-long templating domain.Three telomerases with completely non-telomeric template replacements are catalytically active.Template requirements for telomerase translocation in Kluyveromyces lactis.Mutant telomere sequences lead to impaired chromosome separation and a unique checkpoint response.Telomere shortening, telomerase expression, and chromosome instability in rat hepatic epithelial stem-like cells.Variable telomeric repeat synthesis in Paramecium tetraurelia is consistent with misincorporation by telomerase.A novel specificity for the primer-template pairing requirement in Tetrahymena telomerase.
P2860
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P2860
Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Specific RNA residue interacti ...... ons of Tetrahymena telomerase.
@ast
Specific RNA residue interacti ...... ons of Tetrahymena telomerase.
@en
type
label
Specific RNA residue interacti ...... ons of Tetrahymena telomerase.
@ast
Specific RNA residue interacti ...... ons of Tetrahymena telomerase.
@en
prefLabel
Specific RNA residue interacti ...... ons of Tetrahymena telomerase.
@ast
Specific RNA residue interacti ...... ons of Tetrahymena telomerase.
@en
P2860
P356
P1476
Specific RNA residue interacti ...... ons of Tetrahymena telomerase.
@en
P2093
P2860
P356
10.1128/MCB.16.1.66
P407
P577
1996-01-01T00:00:00Z