SMG5-PNRC2 is functionally dominant compared with SMG5-SMG7 in mammalian nonsense-mediated mRNA decay.
about
Non-structural protein 1 of influenza viruses inhibits rapid mRNA degradation mediated by double-stranded RNA-binding protein, staufen1Nonsense-mediated mRNA decay: novel mechanistic insights and biological impactNonsense-mediated mRNA decay in humans at a glanceNonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryOrganizing principles of mammalian nonsense-mediated mRNA decayThe mRNP remodeling mediated by UPF1 promotes rapid degradation of replication-dependent histone mRNA.A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD.When a ribosome encounters a premature termination codon.Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes.MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1.Identification of SMG6 cleavage sites and a preferred RNA cleavage motif by global analysis of endogenous NMD targets in human cells.Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics.Glucocorticoid receptor interacts with PNRC2 in a ligand-dependent manner to recruit UPF1 for rapid mRNA degradation.Identification of Interactions in the NMD Complex Using Proximity-Dependent Biotinylation (BioID).MicroRNA 433 regulates nonsense-mediated mRNA decay by targeting SMG5 mRNA.Target Discrimination in Nonsense-Mediated mRNA Decay Requires Upf1 ATPase ActivityHyperphosphorylation amplifies UPF1 activity to resolve stalls in nonsense-mediated mRNA decay.Identification and molecular characterization of cellular factors required for glucocorticoid receptor-mediated mRNA decayComparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathwaysVirus Escape and Manipulation of Cellular Nonsense-Mediated mRNA DecayTranslation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3' UTRs.Mechanism, factors, and physiological role of nonsense-mediated mRNA decay.Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes.Control of gene expression through the nonsense-mediated RNA decay pathway.Assessing the activity of nonsense-mediated mRNA decay in lung cancer.The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2.SMG1 is an ancient nonsense-mediated mRNA decay effector.Pnrc2 regulates 3'UTR-mediated decay of segmentation clock-associated transcripts during zebrafish segmentation.Dissecting the functions of SMG5, SMG7 and PNRC2 in nonsense-mediated mRNA decay of human cells.p-4S-UPF1 recruits SMG5; SMG7; SMG6; PNRC2; DCP1A; and PP2A
P2860
Q24294204-1E3E84B4-8ED2-420C-8D76-ACF32CA94373Q26750271-2F82931F-69F4-4891-862F-AAD6972E8FBAQ28077157-0E4D9EBD-9C36-4560-8741-144FAAA3A4ABQ28082699-4641D5C6-524F-4132-A129-54D475EF66FFQ28302705-08248C93-6796-4B5E-9BFA-C964F7F61F64Q34044351-FC80701D-9486-4DD1-B1C9-890F26D1F542Q34044484-4A668414-9624-4FAE-905B-119946A030DFQ34049225-D3609BFB-41FD-49A5-B75C-EC0A7AA75F39Q34518964-9E359E52-E08A-4B12-8CFA-F3625C3ED928Q34797975-53854CF1-2F5A-4305-8F9A-C79A69208BABQ34883031-24CB69E9-F1C2-4CC9-9430-2549D76D1802Q35222320-B00B639F-F577-4E0B-92FE-2320DB410D0AQ35280346-64375589-71A2-4880-8A41-19BAA94942BAQ35942822-21806900-018E-4AC1-8C7C-1AC4557BD7B6Q36090334-A1CBA9C4-FCB4-4616-A7EF-F78B6467811AQ36358461-A56BBEA0-59E3-4E58-9B15-2E9CD580B0E0Q37181245-6BA01245-FF34-47A0-9493-492F236F9D7BQ37343813-810A0B1A-306D-4AD1-8362-E5C14DC0381FQ37371781-41EFA6D3-1168-4D1E-AC6D-B94F3F2E6FA5Q37628239-7D9E973D-054A-4871-967A-D94ABD70CA74Q38314317-7352B9A8-DBC8-461B-BD2C-A8EFA6EE834AQ38568755-52AC222F-D942-412C-B14F-11D0C523EFCBQ38591386-2167C7E8-C303-4E3B-980D-8B1EDBF10235Q39323825-B2D2B4EC-916C-4309-A17B-7DB9CD3FC366Q41625526-06D60A0F-D82B-4BD0-B6B4-9CE7E76854ABQ42848354-FD792B71-6AB8-405E-83C9-75DC70ADFC59Q45928147-E8C60CFE-9F47-46F7-BF64-F522C42942DFQ46713018-6F50C7A6-E923-4A93-B470-A7BB5886ECBAQ48216852-7CBD4667-05E1-470C-A12F-64481D8E13F2Q50295874-5442F4CC-1847-40EA-95D4-E324050D5CD2
P2860
SMG5-PNRC2 is functionally dominant compared with SMG5-SMG7 in mammalian nonsense-mediated mRNA decay.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
SMG5-PNRC2 is functionally dom ...... nonsense-mediated mRNA decay.
@ast
SMG5-PNRC2 is functionally dom ...... nonsense-mediated mRNA decay.
@en
type
label
SMG5-PNRC2 is functionally dom ...... nonsense-mediated mRNA decay.
@ast
SMG5-PNRC2 is functionally dom ...... nonsense-mediated mRNA decay.
@en
prefLabel
SMG5-PNRC2 is functionally dom ...... nonsense-mediated mRNA decay.
@ast
SMG5-PNRC2 is functionally dom ...... nonsense-mediated mRNA decay.
@en
P2093
P2860
P356
P1476
SMG5-PNRC2 is functionally dom ...... nonsense-mediated mRNA decay.
@en
P2093
Junho Choe
Seung Gu Park
Sun Shim Choi
P2860
P304
P356
10.1093/NAR/GKS1222
P407
P577
2012-12-11T00:00:00Z