Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes.
about
A role of DNA-PK for the metabolic gene regulation in response to insulinGenomic structure of mouse and human genes for DNA-PKcs interacting protein (KIP)Carboxyl-terminal region conserved among phosphoinositide-kinase-related kinases is indispensable for mTOR function in vivo and in vitroKu70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombinationDNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptaseFunctional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombinationInteraction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acidsMolecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20DNA-Dependent protein kinase is not required for efficient lentivirus integrationWortmannin potentiates integrase-mediated killing of lymphocytes and reduces the efficiency of stable transduction by retroviruses.Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation.Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development.Failure of hairpin-ended and nicked DNA To activate DNA-dependent protein kinase: implications for V(D)J recombinationp53 regulation by post-translational modification and nuclear retention in response to diverse stresses.Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition.DNA-PKcs is critical for telomere cappingDouble-stranded-RNA-activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53The p53 response to DNA damage in vivo is independent of DNA-dependent protein kinaseIrradiation promotes V(D)J joining and RAG-dependent neoplastic transformation in SCID T-cell precursors.The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.XR-C1, a new CHO cell mutant which is defective in DNA-PKcs, is impaired in both V(D)J coding and signal joint formation.Formation of coding joints in V(D)J recombination-inducible severe combined immune deficient pre-B cell lines.Catalytic subunit of DNA-dependent protein kinase: impact on lymphocyte development and tumorigenesis.Effect of DNA-dependent protein kinase on the molecular fate of the rAAV2 genome in skeletal muscle.Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase.Unique and redundant functions of ATM and DNA-PKcs during V(D)J recombinationDNA damage induces phosphorylation of the amino terminus of p53Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining.The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombinationThe role of the non-homologous end-joining pathway in lymphocyte development.Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency miceGenes, pathways and checkpoints in lymphocyte development and homeostasis.DNA-dependent protein kinase activity is not required for immunoglobulin class switching.Ku70 is required for late B cell development and immunoglobulin heavy chain class switching.Unexpected rearrangement and expression of the immunoglobulin lambda1 locus in scid mice.Fixing DNA breaks during class switch recombination.DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombinationEvidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle.Minisatellite instability in severe combined immunodeficiency mouse cellsLack of genomic instability in bone marrow cells of SCID mice exposed whole-body to low-dose radiation.
P2860
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P2860
Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Biochemical and genetic defect ...... se in murine scid lymphocytes.
@ast
Biochemical and genetic defect ...... se in murine scid lymphocytes.
@en
type
label
Biochemical and genetic defect ...... se in murine scid lymphocytes.
@ast
Biochemical and genetic defect ...... se in murine scid lymphocytes.
@en
prefLabel
Biochemical and genetic defect ...... se in murine scid lymphocytes.
@ast
Biochemical and genetic defect ...... se in murine scid lymphocytes.
@en
P2093
P2860
P356
P1476
Biochemical and genetic defect ...... se in murine scid lymphocytes.
@en
P2093
Holland DP
Mariathasan S
Williams KM
P2860
P304
P356
10.1128/MCB.16.10.5507
P407
P577
1996-10-01T00:00:00Z