Mice with reduced levels of p53 protein exhibit the testicular giant-cell degenerative syndrome. - Wikidata - awgldk - TriplyDB

Mice with reduced levels of p53 protein exhibit the testicular giant-cell degenerative syndrome.

Mice with reduced levels of p53 protein exhibit the testicular giant-cell degenerative syndrome.

http://www.wikidata.org/entity/Q36570848

about

The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2 Interaction of p53 with the human Rad51 protein Targeted disruption of Ing2 results in defective spermatogenesis and development of soft-tissue sarcomas Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control Expression of Tas1 taste receptors in mammalian spermatozoa: functional role of Tas1r1 in regulating basal Ca²⁺ and cAMP concentrations in spermatozoa CREM: a master-switch regulating the balance between differentiation and apoptosis in male germ cells Cell death by mitotic catastrophe: a molecular definition Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation Deletion of genes implicated in protecting the integrity of male germ cells has differential effects on the incidence of DNA breaks and germ cell loss SPATA18, a spermatogenesis-associated gene, is a novel transcriptional target of p53 and p63 Ghrelin Prevents Cisplatin-Induced Testicular Damage by Facilitating Repair of DNA Double Strand Breaks Through Activation of p53 in Mice.Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo Meiotic recombination provokes functional activation of the p53 regulatory network.NGF-mediated transcriptional targets of p53 in PC12 neuronal differentiation.p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals.Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis.The role of p53 gene family in reproduction.A p53-Pax2 pathway in kidney development: implications for nephrogenesis.Single cell monitoring of growth arrest and morphological changes induced by transfer of wild-type p53 alleles to glioblastoma cells.Regulation of Fertility by the p53 Family Members.p53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome.shRNA off-target effects in vivo: impaired endogenous siRNA expression and spermatogenic defects.DNA fragmentation, mitochondrial dysfunction and chromosomal aneuploidy in the spermatozoa of oligoasthenoteratozoospermic males.Quantitative analysis of male germline stem cell differentiation reveals a role for the p53-mTORC1 pathway in spermatogonial maintenance.Apoptotic cell death induced by low-dose radiation in male germ cells: hormesis and adaptation.Genetic variants in TP53 and MDM2 associated with male infertility in Chinese population.Protein partners of deubiquitinating enzymes.Parent-of-origin effects of A1CF and AGO2 on testicular germ-cell tumors, testicular abnormalities, and fertilization bias.Embryonic stem cells shed new light on the developmental roles of p53.Dysregulation of Notch and ERα signaling in AhR-/- male mice.Intrinsically disordered regions of p53 family are highly diversified in evolution.The p53-like Protein CEP-1 Is Required for Meiotic Fidelity in C. elegans The MDM2-p53 pathway: multiple roles in kidney development.Diet-induced obesity impairs spermatogenesis: a potential role for autophagy.p53-family proteins and their regulators: hubs and spokes in tumor suppression.p53 is balancing development, differentiation and de-differentiation to assure cancer prevention.The paradigm of mutant p53-expressing cancer stem cells and drug resistance.Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease?

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P2860

Mice with reduced levels of p53 protein exhibit the testicular giant-cell degenerative syndrome.

http://www.wikidata.org/entity/Q36570848

description

1993 nî lūn-bûn

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1993年の論文

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1993年論文

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1993年論文

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1993年論文

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1993年論文

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1993年論文

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1993年论文

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1993年论文

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1993年论文

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Mice with reduced levels of p5 ...... nt-cell degenerative syndrome.

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Mice with reduced levels of p5 ...... nt-cell degenerative syndrome.

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type

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Mice with reduced levels of p5 ...... nt-cell degenerative syndrome.

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Mice with reduced levels of p5 ...... nt-cell degenerative syndrome.

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Mice with reduced levels of p5 ...... nt-cell degenerative syndrome.

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Mice with reduced levels of p5 ...... nt-cell degenerative syndrome.

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PNAS.90.19.9075

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Mice with reduced levels of p5 ...... nt-cell degenerative syndrome.

@en

P2093

Almon E

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Donehower LA

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Goldfinger N

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Kapon A

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Levine AJ

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Rotter V

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Schwartz D

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P2860

Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox

UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells

Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1

p53 mutations in human cancers

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

Cancer. p53, guardian of the genome

Participation of p53 protein in the cellular response to DNA damage

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

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9075-9079

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90

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14782965

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8415656

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47504

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