Severe obesity and insulin resistance due to deletion of the maternal Gsalpha allele is reversed by paternal deletion of the Gsalpha imprint control region.
about
Gene Dosage Effects at the Imprinted Gnas ClusterFolate deficiency during early-mid pregnancy affects the skeletal muscle transcriptome of piglets from a reciprocal crossMaternal inheritance of the Gnas cluster mutation Ex1A-T affects size, implicating NESP55 in growthGsα deficiency in the dorsomedial hypothalamus underlies obesity associated with Gsα mutations.Successful computational prediction of novel imprinted genes from epigenomic features.Genetic effects at pleiotropic loci are context-dependent with consequences for the maintenance of genetic variation in populations.The role of GNAS and other imprinted genes in the development of obesity.Genetic, epigenetic, and gene-by-diet interaction effects underlie variation in serum lipids in a LG/JxSM/J murine modelThe role of genomic imprinting in biology and disease: an expanding view.Lack of cAMP-response element-binding protein 1 in the hypothalamus causes obesity.Effects of deficiency of the G protein Gsα on energy and glucose homeostasisPediatric obesity: etiology and treatment.Alteration in Expression and Methylation of IGF2/H19 in Placenta and Umbilical Cord Blood Are Associated with Macrosomia Exposed to Intrauterine Hyperglycemia.Analysis of Multiple Families With Single Individuals Affected by Pseudohypoparathyroidism Type Ib (PHP1B) Reveals Only One Novel Maternally Inherited GNAS DeletionThe importance of context to the genetic architecture of diabetes-related traits is revealed in a genome-wide scan of a LG/J × SM/J murine model.Central nervous system imprinting of the G protein G(s)alpha and its role in metabolic regulation.Epigenetics and obesity.Maternal influence of prolyl endopeptidase on fat mass of adult progeny.New Perspectives on Genomic Imprinting, an Essential and Multifaceted Mode of Epigenetic Control in the Developing and Adult Brain.Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 DiabetesPediatric obesity: etiology and treatment.
P2860
Q27316512-6B1F61BD-B8CD-402D-B704-0CE139EAA993Q27342732-DB7D4476-7E76-4379-A27F-424D1BFCBBF3Q28592629-6A3334EA-2C6F-4DE1-B49B-2733EFC02C78Q30352984-5C4928E2-3D77-4AC8-9E69-85E590623DD6Q33963896-4E5C08CC-8983-4A93-BFF6-4F13709F423CQ34023030-752C7126-03B0-4C9E-8CFE-32F6621B6214Q34099397-63EC5964-1116-4FD7-961F-1D57A79D9866Q34116418-B0853EED-DB98-4C92-9EBB-EAD783DBC68AQ34426232-18541635-CC70-4263-A0A9-2361631FD87CQ34624262-5228CA7D-5422-4E78-BE07-25067C738EF3Q34883776-CBAD5AC1-094A-448A-BDA4-B7832E950B9CQ35678445-A0BF5051-4121-4190-8469-C07CEDA5FE43Q35913006-7089F1CC-8C26-46C7-B97B-9D00627B81CEQ36784438-B6A56F93-813E-4B58-BB50-4A1622E82E0FQ36834134-4A8B99DB-BBCD-4EDB-A504-B0DE015154F2Q37233680-9D1C89E8-95E9-4D08-817A-CA3AAD60461FQ37346204-6F5D79A4-2150-4CF4-BB4B-D9F2FBAE4D02Q37346305-A00C35B0-3E5C-49C7-88BB-39C09A6A32F2Q37445958-242AC278-D147-4EFB-B728-8165D9EF9278Q38803129-574B2E1C-389B-4C35-9661-CDDD5D903617Q42096028-E4954BFF-00FD-4801-9F57-CE46ED03158F
P2860
Severe obesity and insulin resistance due to deletion of the maternal Gsalpha allele is reversed by paternal deletion of the Gsalpha imprint control region.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Severe obesity and insulin res ...... salpha imprint control region.
@ast
Severe obesity and insulin res ...... salpha imprint control region.
@en
type
label
Severe obesity and insulin res ...... salpha imprint control region.
@ast
Severe obesity and insulin res ...... salpha imprint control region.
@en
prefLabel
Severe obesity and insulin res ...... salpha imprint control region.
@ast
Severe obesity and insulin res ...... salpha imprint control region.
@en
P2093
P2860
P356
P1433
P1476
Severe obesity and insulin res ...... salpha imprint control region.
@en
P2093
Edwin W Lai
Oksana Gavrilova
P2860
P304
P356
10.1210/EN.2007-1458
P407
P577
2008-01-17T00:00:00Z