BTKbase: the mutation database for X-linked agammaglobulinemia.
about
Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responsesStructures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinasesResistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinibSecond-generation inhibitors of Bruton tyrosine kinasePhylogenetic Profiles Reveal Structural and Functional Determinants of Lipid-bindingSH2-dependent autophosphorylation within the Tec family kinase Itk.The structural basis of hyper IgM deficiency - CD40L mutations.Characterization of all possible single-nucleotide change caused amino acid substitutions in the kinase domain of Bruton tyrosine kinase.Spectrum of disease-causing mutations in protein secondary structuresThe energy landscape analysis of cancer mutations in protein kinasesSequence and structure signatures of cancer mutation hotspots in protein kinasesClinical targeting of mutated and wild-type protein tyrosine kinases in cancer.Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases.Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia modelInhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity and inflammatory diseases.B lymphocytes: how they develop and function.A novel Bruton's tyrosine kinase gene (BTK) missense mutation in a Chinese family with X-linked agammaglobulinemia.Atypical X-linked agammaglobulinaemia caused by a novel BTK mutation in a selective immunoglobulin M deficiency patient.Splice-correction strategies for treatment of X-linked agammaglobulinemia.Tubulointerstitial nephritis complicating IVIG therapy for X-linked agammaglobulinemiaVariOtator, a Software Tool for Variation Annotation with the Variation Ontology.Human Variome Project Quality Assessment Criteria for Variation Databases.X-linked agammaglobulinemia diagnosed late in life: case report and review of the literature.Adult-onset presentations of genetic immunodeficiencies: genes can throw slow curves.Three newly approved drugs for chronic lymphocytic leukemia: incorporating ibrutinib, idelalisib, and obinutuzumab into clinical practice.Genetic predispositions to childhood leukemia.The genetic theory of infectious diseases: a brief history and selected illustrations.Comprehensive genetic testing for primary immunodeficiency disorders in a tertiary hospital: 10-year experience in Auckland, New ZealandGenetics of hypogammaglobulinemia: what do we really know?Recurrent somatic mutations affecting B-cell receptor signaling pathway genes in follicular lymphoma.Neutropenia and primary immunodeficiency diseases.TEC family kinases in health and disease--loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK.BMX and its role in inflammation, cardiovascular disease, and cancer.Agammaglobulinemia: causative mutations and their implications for novel therapies.Bruton's tyrosine kinase--an integral protein of B cell development that also has an essential role in the innate immune system.Breaking good: the inexorable rise of BTK inhibitors in the treatment of chronic lymphocytic leukaemia.The role of Bruton's tyrosine kinase in autoimmunity and implications for therapy.PON-P and PON-P2 predictor performance in CAGI challenges: Lessons learned.Substitution scanning identifies a novel, catalytically active ibrutinib-resistant BTK cysteine 481 to threonine (C481T) variant.From identification of the BTK kinase to effective management of leukemia.
P2860
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P2860
BTKbase: the mutation database for X-linked agammaglobulinemia.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
BTKbase: the mutation database for X-linked agammaglobulinemia.
@ast
BTKbase: the mutation database for X-linked agammaglobulinemia.
@en
type
label
BTKbase: the mutation database for X-linked agammaglobulinemia.
@ast
BTKbase: the mutation database for X-linked agammaglobulinemia.
@en
prefLabel
BTKbase: the mutation database for X-linked agammaglobulinemia.
@ast
BTKbase: the mutation database for X-linked agammaglobulinemia.
@en
P356
P1433
P1476
BTKbase: the mutation database for X-linked agammaglobulinemia
@en
P2093
Jouni Väliaho
P2860
P304
P356
10.1002/HUMU.20410
P577
2006-12-01T00:00:00Z