Regulation and targeting of recombination in extrachromosomal substrates carrying immunoglobulin switch region sequences
about
Cux/CDP homeoprotein is a component of NF-muNR and represses the immunoglobulin heavy chain intronic enhancer by antagonizing the bright transcription activatorProcessing of switch transcripts is required for targeting of antibody class switch recombination.Extrachromosomal recombination occurs efficiently in cells defective in various DNA repair systemsSequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Smu class switch regionEvidence for class-specific factors in immunoglobulin isotype switchingThe mu switch region tandem repeats are important, but not required, for antibody class switch recombination.A specific isoform of hnRNP D interacts with DNA in the LR1 heterodimer: canonical RNA binding motifs in a sequence-specific duplex DNA binding protein.A transcriptional serenAID: the role of noncoding RNAs in class switch recombination.The microsatellite sequence (CT)n x (GA)n promotes stable chromosomal integration of large tandem arrays of functional human U2 small nuclear RNA genes.Asymmetric mutation around the recombination break point of immunoglobulin class switch sequences on extrachromosomal substrates.Adenovirus type 12-induced fragility of the human RNU2 locus requires U2 small nuclear RNA transcriptional regulatory elements.Efficient AID targeting of switch regions is not sufficient for optimal class switch recombination.An extrachromosomal switch recombination substrate reveals kinetics and substrate requirements of switch recombination in primary murine B cells.
P2860
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P2860
Regulation and targeting of recombination in extrachromosomal substrates carrying immunoglobulin switch region sequences
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Regulation and targeting of re ...... obulin switch region sequences
@ast
Regulation and targeting of re ...... obulin switch region sequences
@en
type
label
Regulation and targeting of re ...... obulin switch region sequences
@ast
Regulation and targeting of re ...... obulin switch region sequences
@en
prefLabel
Regulation and targeting of re ...... obulin switch region sequences
@ast
Regulation and targeting of re ...... obulin switch region sequences
@en
P2860
P356
P1476
Regulation and targeting of re ...... obulin switch region sequences
@en
P2093
P2860
P304
P356
10.1128/MCB.14.2.1450
P407
P577
1994-02-01T00:00:00Z