Evidence for class-specific factors in immunoglobulin isotype switching
about
Imprinting the fate of antigen-reactive B cells through the affinity of the B cell receptor.Evolution of antibody class switching: identification and transcriptional control of an Inu exon in the duck (Anas platyrhynchos).Influence of switch region length on immunoglobulin class switch recombination.Mechanism and regulation of class switch recombinationAID to overcome the limitations of genomic information by introducing somatic DNA alterations.Accessibility control and machinery of immunoglobulin class switch recombination.Class-switch recombination: after the dawn of AID.The mu switch region tandem repeats are important, but not required, for antibody class switch recombination.Mapping of a functional recombination motif that defines isotype specificity for mu-->gamma3 switch recombination implicates NF-kappaB p50 as the isotype-specific switching factorTwo new isotype-specific switching activities detected for Ig class switching.Sgamma3 switch sequences function in place of endogenous Sgamma1 to mediate antibody class switchingNF-kappa B p50-dependent in vivo footprints at Ig S gamma 3 DNA are correlated with mu-->gamma 3 switch recombinationS-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase.Identification of murine B cell lines that undergo somatic hypermutation focused to A:T and G:C residues.Switch region identity plays an important role in Ig class switch recombination.NF-kappa B binds to the immunoglobulin S gamma 3 region in vivo during class switch recombination.Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidneyAID-dependent histone acetylation is detected in immunoglobulin S regions.Efficient AID targeting of switch regions is not sufficient for optimal class switch recombination.
P2860
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P2860
Evidence for class-specific factors in immunoglobulin isotype switching
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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name
Evidence for class-specific factors in immunoglobulin isotype switching
@ast
Evidence for class-specific factors in immunoglobulin isotype switching
@en
type
label
Evidence for class-specific factors in immunoglobulin isotype switching
@ast
Evidence for class-specific factors in immunoglobulin isotype switching
@en
prefLabel
Evidence for class-specific factors in immunoglobulin isotype switching
@ast
Evidence for class-specific factors in immunoglobulin isotype switching
@en
P2093
P2860
P356
P1476
Evidence for class-specific factors in immunoglobulin isotype switching
@en
P2093
P2860
P304
P356
10.1084/JEM.191.8.1365
P407
P577
2000-04-01T00:00:00Z