Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras
about
Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEFA novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiaeIdentification of a novel guanine nucleotide exchange factor for the Rho GTPaseCDC42 and FGD1 cause distinct signaling and transforming activities.Regulatory and signaling properties of the Vav familyCloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Rasp95vav associates with the nuclear protein Ku-70Association of the vav proto-oncogene product with poly(rC)-specific RNA-binding proteinsRole of the vav proto-oncogene product (Vav) in erythropoietin-mediated cell proliferation and phosphatidylinositol 3-kinase activitySos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptorsThe tyrosine phosphatase PTP1C associates with Vav, Grb2, and mSos1 in hematopoietic cellsT cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21rasGuanine nucleotide exchange factors: activators of the Ras superfamily of proteinsLck regulates Vav activation of members of the Rho family of GTPasesApoptosis: molecular regulation of cell deathp95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cellsVav: function and regulation in hematopoietic cell signaling.G2A is an oncogenic G protein-coupled receptor.A role for Rho in Ras transformation.Tyrosine phosphorylation of Dbl regulates GTPase signalingA rac homolog is required for induction of hyphal growth in the dimorphic yeast Yarrowia lipolytica.Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stressSignal transduction in T lymphocytes using a conditional allele of SosDependence of Dbl and Dbs transformation on MEK and NF-kappaB activation.Autoinhibition mechanism of proto-Dbl.Calcineurin inhibitor-induced and Ras-mediated overexpression of VEGF in renal cancer cells involves mTOR through the regulation of PRAS40Transformation by a nucleotide-activated P2Y receptor is mediated by activation of Galphai, Galphaq and Rho-dependent signaling pathways.Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins.Opposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Ras-mediated downregulation of tropomyosin.RhoGEF specificity mutants implicate RhoA as a target for Dbs transforming activity.Insulin-dependent tyrosine phosphorylation of the vav protooncogene product in cells of hematopoietic origin.Vav is necessary for prolactin-stimulated proliferation and is translocated into the nucleus of a T-cell line.The heme oxygenase-1 protein is overexpressed in human renal cancer cells following activation of the Ras-Raf-ERK pathway and mediates anti-apoptotic signal.A role for Pak protein kinases in Schwann cell transformation.Vav regulates peptide-specific apoptosis in thymocytesLipid rafts in lymphocyte activation and migration.A functional T-cell receptor signaling pathway is required for p95vav activity.Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation.Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation.
P2860
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P2860
Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Dbl and Vav mediate transforma ...... ose activated by oncogenic Ras
@ast
Dbl and Vav mediate transforma ...... ose activated by oncogenic Ras
@en
type
label
Dbl and Vav mediate transforma ...... ose activated by oncogenic Ras
@ast
Dbl and Vav mediate transforma ...... ose activated by oncogenic Ras
@en
prefLabel
Dbl and Vav mediate transforma ...... ose activated by oncogenic Ras
@ast
Dbl and Vav mediate transforma ...... ose activated by oncogenic Ras
@en
P2093
P2860
P356
P1476
Dbl and Vav mediate transforma ...... ose activated by oncogenic Ras
@en
P2093
K Burridge
M Chrzanowska-Wodnicka
P A Solski
R Khosravi-Far
P2860
P304
P356
10.1128/MCB.14.10.6848
P407
P577
1994-10-01T00:00:00Z