Structural and functional dissection of Sec62p, a membrane-bound component of the yeast endoplasmic reticulum protein import machinery.
about
Topological and mutational analysis of Saccharomyces cerevisiae Ste14p, founding member of the isoprenylcysteine carboxyl methyltransferase familyVma21p is a yeast membrane protein retained in the endoplasmic reticulum by a di-lysine motif and is required for the assembly of the vacuolar H(+)-ATPase complexSec72p contributes to the selective recognition of signal peptides by the secretory polypeptide translocation complex.Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23pSignal recognition particle receptor is important for cell growth and protein secretion in Saccharomyces cerevisiae.Different subcellular localization of Saccharomyces cerevisiae HMG-CoA reductase isozymes at elevated levels corresponds to distinct endoplasmic reticulum membrane proliferations.A novel Hsp70 of the yeast ER lumen is required for the efficient translocation of a number of protein precursorsYeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis.Smy2p participates in COPII vesicle formation through the interaction with Sec23p/Sec24p subcomplex.A functional GTPase domain, but not its transmembrane domain, is required for function of the SRP receptor beta-subunit.CWH41 encodes a novel endoplasmic reticulum membrane N-glycoprotein involved in beta 1,6-glucan assembly.Characterization of YDJ1: a yeast homologue of the bacterial dnaJ proteinSMS1, a high-copy suppressor of the yeast mas6 mutant, encodes an essential inner membrane protein required for mitochondrial protein import.Bud8p and Bud9p, proteins that may mark the sites for bipolar budding in yeast.Saccharomyces cerevisiae Big1p, a putative endoplasmic reticulum membrane protein required for normal levels of cell wall beta-1,6-glucan.Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum.Sec61p serves multiple roles in secretory precursor binding and translocation into the endoplasmic reticulum membrane.Efficient export of the glucose transporter Hxt1p from the endoplasmic reticulum requires Gsf2p.The PBN1 gene of Saccharomyces cerevisiae: an essential gene that is required for the post-translational processing of the protease B precursorCharacterization of a novel ADP-ribosylation factor-like protein (yARL3) in Saccharomyces cerevisiae.Genes that control the fidelity of endoplasmic reticulum to Golgi transport identified as suppressors of vesicle budding mutations.A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposomeTwo alternative binding mechanisms connect the protein translocation Sec71-Sec72 complex with heat shock proteins.Alpha-synuclein-induced aggregation of cytoplasmic vesicles in Saccharomyces cerevisiaeEvolutionary gain of function for the ER membrane protein Sec62 from yeast to humansN-terminal acetylation inhibits protein targeting to the endoplasmic reticulumA 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins.Split ubiquitin as a sensor of protein interactions in vivo.Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase.Two active states of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity.Reconstitution of protein translocation from solubilized yeast membranes reveals topologically distinct roles for BiP and cytosolic Hsc70.Interaction between BiP and Sec63p is required for the completion of protein translocation into the ER of Saccharomyces cerevisiae.Signal sequences specify the targeting route to the endoplasmic reticulum membraneMutants in three novel complementation groups inhibit membrane protein insertion into and soluble protein translocation across the endoplasmic reticulum membrane of Saccharomyces cerevisiaeStructural and functional dissection of a membrane glycoprotein required for vesicle budding from the endoplasmic reticulumDetection of transient in vivo interactions between substrate and transporter during protein translocation into the endoplasmic reticulumSuppression of a sec63 mutation identifies a novel component of the yeast endoplasmic reticulum translocation apparatus.Genetic interactions between KAR2 and SEC63, encoding eukaryotic homologues of DnaK and DnaJ in the endoplasmic reticulum.A Sec62p-related component of the secretory protein translocon from Drosophila displays developmentally complex behaviorProtein O-mannosyltransferases associate with the translocon to modify translocating polypeptide chains.
P2860
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P2860
Structural and functional dissection of Sec62p, a membrane-bound component of the yeast endoplasmic reticulum protein import machinery.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Structural and functional diss ...... ulum protein import machinery.
@ast
Structural and functional diss ...... ulum protein import machinery.
@en
type
label
Structural and functional diss ...... ulum protein import machinery.
@ast
Structural and functional diss ...... ulum protein import machinery.
@en
prefLabel
Structural and functional diss ...... ulum protein import machinery.
@ast
Structural and functional diss ...... ulum protein import machinery.
@en
P2860
P356
P1476
Structural and functional diss ...... ulum protein import machinery.
@en
P2093
R J Deshaies
P2860
P304
P356
10.1128/MCB.10.11.6024
P407
P577
1990-11-01T00:00:00Z