Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface.
about
Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptorDefining the directionality and quality of influenza virus-specific CD8+ T cell cross-reactivity in individuals infected with hepatitis C virusIdentifying Individual T Cell Receptors of Optimal Avidity for Tumor AntigensLower Affinity T Cells are Critical Components and Active Participants of the Immune ResponseThe multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cellsThe promise of γδ T cells and the γδ T cell receptor for cancer immunotherapyMore tricks with tetramers: a practical guide to staining T cells with peptide-MHC multimersStructural Basis of the CD8 /MHC Class I Interaction: Focused Recognition Orients CD8 to a T Cell Proximal PositionT-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen TargetingEngineering and characterization of a stabilized alpha1/alpha2 module of the class I major histocompatibility complex product Ld.High-affinity TCRs generated by phage display provide CD4+ T cells with the ability to recognize and kill tumor cell lines.Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognitionEngineering superior DNA vaccines: MHC class I single chain trimers bypass antigen processing and enhance the immune response to low affinity antigens.The impact of TCR-binding properties and antigen presentation format on T cell responsiveness.Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells.Identification of new MUC1 epitopes using HLA-transgenic animals: implication for immunomonitoring.CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptorThe nucleocapsid protein of Rift Valley fever virus is a potent human CD8+ T cell antigen and elicits memory responsesProtein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramersAntibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRsAnti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining.Phenotypic and functional evaluation of CD3+CD4-CD8- T cells in human CD8 immunodeficiency.T cell receptor binding affinity governs the functional profile of cancer-specific CD8+ T cellsInteraction of streptavidin-based peptide-MHC oligomers (tetramers) with cell-surface TCRsReversible major histocompatibility complex I-peptide multimers containing Ni(2+)-nitrilotriacetic acid peptides and histidine tags improve analysis and sorting of CD8(+) T cellsDistortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer PeptideInsights into T cell recognition of antigen: significance of two-dimensional kinetic parametersExpansion of Simian Immunodeficiency Virus (SIV)-Specific CD8 T Cell Lines from SIV-Naive Mauritian Cynomolgus Macaques for Adoptive Transfer.Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence.Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability.Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes.Modulation of MHC binding by lateral association of TCR and coreceptor.Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA virusesAvailability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitopeStructural determinants of T-cell receptor bias in immunity.Quantitative theories of T-cell responsiveness.Functional development of the T cell receptor for antigenHotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8+ T cells with peptide-major histocompatibility complex class I tetramers.
P2860
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P2860
Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Interaction between the CD8 co ...... complexes at the cell surface.
@ast
Interaction between the CD8 co ...... complexes at the cell surface.
@en
type
label
Interaction between the CD8 co ...... complexes at the cell surface.
@ast
Interaction between the CD8 co ...... complexes at the cell surface.
@en
prefLabel
Interaction between the CD8 co ...... complexes at the cell surface.
@ast
Interaction between the CD8 co ...... complexes at the cell surface.
@en
P2093
P2860
P356
P1476
Interaction between the CD8 co ...... complexes at the cell surface.
@en
P2093
Anita Milicic
Bruno Laugel
Daniel C Douek
Emma Gostick
Hugo A van den Berg
Jason M Brenchley
Linda Wooldridge
Meir Glick
Sarah L Hutchinson
P2860
P304
27491-27501
P356
10.1074/JBC.M500555200
P407
P577
2005-04-18T00:00:00Z