The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.
about
ABL tyrosine kinases: evolution of function, regulation, and specificityProtein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo.Two additional protein-tyrosine kinases expressed in human lung: fourth member of the fibroblast growth factor receptor family and an intracellular protein-tyrosine kinaseA direct binding site for Grb2 contributes to transformation and leukemogenesis by the Tel-Abl (ETV6-Abl) tyrosine kinaseTranscriptional activation of a ras-like gene (kir) by oncogenic tyrosine kinasesA DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/MCloned fusion product from a rare t(15;19)(q13.2;p13.1) inhibit S phase in vitroCurrent concepts in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemiaAssociation of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathwayProduction of high-titer helper-free retroviruses by transient transfectionInteractions of p62(dok) with p210(bcr-abl) and Bcr-Abl-associated proteins.Interactions of CBL with BCR-ABL and CRKL in BCR-ABL-transformed myeloid cells.Deletion of the ABL SH3 domain reactivates de-oligomerized BCR-ABL for growth factor independence.Mutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation.En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein tyrosine kinase.BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in miceRecurrent t(2;2) and t(2;8) translocations in rhabdomyosarcoma without the canonical PAX-FOXO1 fuse PAX3 to members of the nuclear receptor transcriptional coactivator family.Inhibition of anchorage-independent growth of transformed NIH3T3 cells by epithelial protein lost in neoplasm (EPLIN) requires localization of EPLIN to actin cytoskeleton.The v-myc oncogene.Temperature-sensitive transformation by an Abelson virus mutant encoding an altered SH2 domain.Signaling by ABL oncogenes through cyclin D1.An E mu-v-abl transgene elicits plasmacytomas in concert with an activated myc gene.Dual transforming activities of the FUS (TLS)-ERG leukemia fusion protein conferred by two N-terminal domains of FUS (TLS).Mechanisms of cell-cycle checkpoints: at the crossroads of carcinogenesis and drug discovery.Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2.Recent advances in the molecular and cellular biology of chronic myeloid leukaemia: lessons to be learned from the laboratory.Functional analysis of the AUG- and CUG-initiated forms of the c-Myc proteinSignal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia.Myc roles in hematopoiesis and leukemiaStudying the pathogenesis of BCR-ABL+ leukemia in mice.Multiple aromatic side chains within a disordered structure are critical for transcription and transforming activity of EWS family oncoproteins.Inhibition of MAP kinase kinase causes morphological reversion and dissociation between soft agar growth and in vivo tumorigenesis in angiosarcoma cells.FoxO tumor suppressors and BCR-ABL-induced leukemia: a matter of evasion of apoptosis.Leukemia treatment in severe combined immunodeficiency mice by antisense oligodeoxynucleotides targeting cooperating oncogenesEwing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.Activation of abl family kinases in solid tumors.BCR-ABL and v-abl oncogenes induce distinct patterns of thymic lymphoma involving different lymphocyte subsets.SH1 domain autophosphorylation of P210 BCR/ABL is required for transformation but not growth factor independence.Hyperexpression of interleukin-7 is not necessary or sufficient for transformation of a pre-B lymphoid cell line.
P2860
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P2860
The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.
@ast
The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.
@en
type
label
The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.
@ast
The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.
@en
prefLabel
The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.
@ast
The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.
@en
P2860
P356
P1476
The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.
@en
P2093
P2860
P304
P356
10.1128/MCB.9.3.1263
P407
P577
1989-03-01T00:00:00Z