Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival.
about
The enigma of caspase-2: the laymen's viewThe Bcl-2 apoptotic switch in cancer development and therapyCaspase-2 activation in the absence of PIDDosome formationThe BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cellsThe NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cellsPuma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis inductionTranscription factors in late megakaryopoiesis and related platelet disordersApoptosis is essential for neutrophil functional shutdown and determines tissue damage in experimental pneumococcal meningitisSurvival and cell cycle control in early hematopoiesis: role of bcl-2, and the cyclin dependent kinase inhibitors P27 and P21Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosisATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytesActivation of Wnt/β-catenin protein signaling induces mitochondria-mediated apoptosis in hematopoietic progenitor cellsExpression of a Chimeric Antigen Receptor in Multiple Leukocyte Lineages in Transgenic MiceFas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis.Oxygen tension influences the differentiation, maturation and apoptosis of human megakaryocytes.Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets.A megakaryocyte with no platelets: anti-platelet antibodies, apoptosis, and platelet production.Loss of Bak enhances lymphocytosis but does not ameliorate thrombocytopaenia in BCL-2 transgenic mice.Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways.Functional cooperation of the proapoptotic Bcl2 family proteins Bmf and Bim in vivoc-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells.Basal NF-κB controls IL-7 responsiveness of quiescent naïve T cellsExpansion of cord blood CD34 cells in presence of zVADfmk and zLLYfmk improved their in vitro functionality and in vivo engraftment in NOD/SCID mouseNegative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling.Gamma interferon-induced T-cell loss in virulent Mycobacterium avium infection.Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) impairs the regulation of apoptosis in megakaryocytes by activating NF-κB: a proteomic study.c-Rel controls multiple discrete steps in the thymic development of Foxp3+ CD4 regulatory T cells.BH3-only protein Bmf mediates apoptosis upon inhibition of CAP-dependent protein synthesis.Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma developmentMegakaryocytes and beyond: the birth of platelets.The TLX1 oncogene drives aneuploidy in T cell transformationElevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance.Apoptosis and non-inflammatory phagocytosis can be induced by mitochondrial damage without caspases.αβ versus γδ fate choice: counting the T-cell lineages at the branch point.The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance.The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression.Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.The essential role of evasion from cell death in cancer.Regulation of apoptosis by ubiquitination.
P2860
Q24595653-FF1A5244-4726-4316-9232-A4C016032880Q24620437-151E0173-2C0F-4F1E-A87C-0B1A3B77A653Q24641934-CCBB78AE-5293-490D-A202-1A36716E003BQ24650702-4DEE5EDE-CD59-4DB0-BD17-49680EF31AE8Q24676636-92E9577E-AE42-45DC-BCFE-3DEF089BBF0BQ24677017-115B3606-F470-45A9-BA2F-124CC3C5164BQ27015841-A54D859B-D318-4573-9107-AB383908B011Q27316800-BCCC91E4-5EAD-40A3-815A-6EB42C3A7C56Q28209016-F88DAF6C-B984-47BB-A149-BE819F0D7E3EQ28587336-6331DBE7-00E8-428B-8D35-4A98BCC188FEQ28591671-A09BF38F-9666-43C6-81CF-73A9A8F594E8Q30318095-156AC65A-AF66-4510-991E-9D031C6D4606Q30399332-48B0FAC0-98E0-4699-AD18-4340F882AC1EQ30503491-EEE584E3-BA0E-4F93-A4B0-94D4E4568162Q33303491-A90593F5-8BFF-4DB1-8BA6-F8162968CA17Q33335462-702549BF-F918-4F17-9314-45A00FF6D829Q33397149-CCA1B9C8-AA59-4744-A905-445C3AF019A3Q33402025-0864C302-06BF-46C1-8898-451EFD1AF333Q33412907-25E5C23E-3815-447B-986D-7FE408B31D9EQ33413970-65E31193-0EA9-46CB-91FE-454E29BC327EQ33558259-DB2D2BD5-BE4F-48CA-83C8-73183FD476B1Q33590483-60462C0B-DB37-438E-AC9E-9F7C567FB9ECQ33665672-7AF9D3FF-3A3E-4986-881F-BFA14C499E1BQ33680859-59D86215-ECAD-4A6C-B32C-E49835A8AFC8Q33782491-0CB4BF06-4DD8-4F63-8023-05E3B9476C7FQ33788068-20323FCB-012A-45AD-AD3A-8298FCFC9EB5Q34040202-0B48FDFD-EE85-4FA6-BFE3-4F2B1C79A19BQ34069619-85B7A188-DABD-4051-8099-E8E3700C9D1BQ34191999-5D2224F8-920F-4CC1-A9B2-CE9DED19293EQ34192011-2555EB78-87C7-466B-8ACB-72752F9DD16AQ34215516-7D8A5E02-265C-4A21-8A86-03C57353166AQ34283329-FF378C56-FE35-4360-AE73-61D5C8B0AEC3Q34369809-98626A7B-5F7B-467A-B719-E3BB0DDCC564Q34422595-1D6C03D1-F13F-45DF-8947-1828821DEF13Q34540532-ABC6E7A5-0869-4914-8A35-DA88867A0E40Q34681351-9DFBFD29-B8E2-454E-ABE8-0181489529A6Q34682769-7C5D79E6-C138-41CF-B3BA-3E0C82085C67Q35075545-AD351DEF-E192-4AC4-B79B-0D105CE2E03DQ35083049-8CAF2B67-572D-4638-A180-7A3CDB288569Q35129703-BCFCBBDD-F971-4C06-828E-8AB70CF05508
P2860
Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Constitutive Bcl-2 expression ...... nces progenitor cell survival.
@ast
Constitutive Bcl-2 expression ...... nces progenitor cell survival.
@en
type
label
Constitutive Bcl-2 expression ...... nces progenitor cell survival.
@ast
Constitutive Bcl-2 expression ...... nces progenitor cell survival.
@en
prefLabel
Constitutive Bcl-2 expression ...... nces progenitor cell survival.
@ast
Constitutive Bcl-2 expression ...... nces progenitor cell survival.
@en
P2093
P2860
P356
P1476
Constitutive Bcl-2 expression ...... nces progenitor cell survival.
@en
P2093
P2860
P304
14943-14948
P356
10.1073/PNAS.96.26.14943
P407
P577
1999-12-01T00:00:00Z