Mechanisms of translational deregulation in human tumors and therapeutic intervention strategies.
about
Melanoma and the Unfolded Protein ResponseDifferential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: effects of endothelin-1, oxidative stress and cytokinesThe role of PKR/eIF2α signaling pathway in prognosis of non-small cell lung cancerRegulation of the cardiomyocyte transcriptome vs translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulin.Stress-dependent coordination of transcriptome and translatome in yeastThe translation elongation factor eEF2 is a novel tumor‑associated antigen overexpressed in various types of cancers.Targeting the translational machinery as a novel treatment strategy for hematologic malignanciesIntegrated mutation, copy number and expression profiling in resectable non-small cell lung cancer.The tumor suppressive role of eIF3f and its function in translation inhibition and rRNA degradation.When ribosomes go bad: diseases of ribosome biogenesis.Ligand stimulation of ErbB4 and a constitutively-active ErbB4 mutant result in different biological responses in human pancreatic tumor cell lines.Eukaryotic Initiation Factor 4H Is under Transcriptional Control of p65/NF-κB.BRCA1-Dependent Translational Regulation in Breast Cancer Cells.Rapid high-resolution mapping of balanced chromosomal rearrangements on tiling CGH arrays.Computational challenges, tools, and resources for analyzing co- and post-transcriptional events in high throughput.Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogastereIF4E and eIF4GI have distinct and differential imprints on multiple myeloma's proteome and signaling.Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches.Increased susceptibility of breast cancer cells to stress mediated inhibition of protein synthesis.RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growthDissecting eIF4E action in tumorigenesisCandidate pathways for promoting differentiation or quiescence of oligodendrocyte progenitor-like cells in glioma.siRNA screen of the human signaling proteome identifies the PtdIns(3,4,5)P3-mTOR signaling pathway as a primary regulator of transferrin uptakePTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex.Radiation-induced gene translation profiles reveal tumor type and cancer-specific components.Tumor suppressor p16(INK4a) inhibits cancer cell growth by downregulating eEF1A2 through a direct interaction.Post-transcriptional gene regulation: from genome-wide studies to principles.Identification of actively translated mRNA transcripts in a rat model of early-stage colon carcinogenesis.eIF3i activity is critical for endothelial cells in tumor induced angiogenesis through regulating VEGFR and ERK translation.Suppression of vascular endothelial growth factor via inactivation of eukaryotic elongation factor 2 by alkaloids in Coptidis rhizome in hepatocellular carcinoma.Repression of microRNA-768-3p by MEK/ERK signalling contributes to enhanced mRNA translation in human melanoma.Identifying targets for the restoration and reactivation of BRM.Autoantibody response to Sui1 and its tissue-specific expression in hepatocellular carcinoma.Eph receptor and mTOR pathway crosstalk: implications for cancer.NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.Protection against Cancer with Medicinal Herbs via Activation of Tumor SuppressorMany ribosomal protein mutations are associated with growth impairment and tumor predisposition in zebrafish.Oxidative stress perturbs cell proliferation in human K562 cells by modulating protein synthesis and cell cycle.Eukaryotic Elongation Factor 2 (eEF2) is a Potential Biomarker of Prostate Cancer.Hypoxia-mediated translational activation of ITGB3 in breast cancer cells enhances TGF-β signaling and malignant features in vitro and in vivo.
P2860
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P2860
Mechanisms of translational deregulation in human tumors and therapeutic intervention strategies.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Mechanisms of translational de ...... eutic intervention strategies.
@ast
Mechanisms of translational de ...... eutic intervention strategies.
@en
type
label
Mechanisms of translational de ...... eutic intervention strategies.
@ast
Mechanisms of translational de ...... eutic intervention strategies.
@en
prefLabel
Mechanisms of translational de ...... eutic intervention strategies.
@ast
Mechanisms of translational de ...... eutic intervention strategies.
@en
P2860
P356
P1433
P1476
Mechanisms of translational de ...... peutic intervention strategies
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210431
P407
P577
2007-04-02T00:00:00Z