Phospholipase C-linked receptors regulate the ATP-sensitive potassium channel by means of phosphatidylinositol 4,5-bisphosphate metabolism
about
Noble gas xenon is a novel adenosine triphosphate-sensitive potassium channel openerRunning out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channelsRegulation of a G protein-gated inwardly rectifying K+ channel by a Ca(2+)-independent protein kinase CReceptor-mediated inhibition of G protein-coupled inwardly rectifying potassium channels involves G(alpha)q family subunits, phospholipase C, and a readily diffusible messenger.Depletion of phosphatidylinositol 4,5-bisphosphate by activation of phospholipase C-coupled receptors causes slow inhibition but not desensitization of G protein-gated inward rectifier K+ current in atrial myocytes.ATP modulation of ATP-sensitive potassium channel ATP sensitivity varies with the type of SUR subunit.Receptor-induced depletion of phosphatidylinositol 4,5-bisphosphate inhibits inwardly rectifying K+ channels in a receptor-specific mannerKATP channels gated by intracellular nucleotides and phospholipids.The complex and intriguing lives of PIP2 with ion channels and transporters.Regulation of the muscarinic K+ channel by extracellular ATP through membrane phosphatidylinositol 4,5-bisphosphate in guinea-pig atrial myocytesMuscle KATP channels: recent insights to energy sensing and myoprotectionPhosphoinositide control of membrane protein function: a frontier led by studies on ion channels.Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational AnalysisStructural determinants of PIP(2) regulation of inward rectifier K(ATP) channels.Stabilization of the activity of ATP-sensitive potassium channels by ion pairs formed between adjacent Kir6.2 subunits.Hydrolyzable ATP and PIP(2) modulate the small-conductance K+ channel in apical membranes of rat cortical-collecting duct (CCD).Structural and functional determinants of conserved lipid interaction domains of inward rectifying Kir6.2 channelsLong polyamines act as cofactors in PIP2 activation of inward rectifier potassium (Kir2.1) channelsMuscarinic cationic current in gastrointestinal smooth muscles: signal transduction and role in contraction.Cardiac sarcolemmal K(ATP) channels: Latest twists in a questing tale!Channelopathies linked to plasma membrane phosphoinositides.Ca2+ Influx through Store-operated Calcium Channels Replenishes the Functional Phosphatidylinositol 4,5-Bisphosphate Pool Used by Cysteinyl Leukotriene Type I Receptors.Dynamic sensitivity of ATP-sensitive K(+) channels to ATP.PIP2 PIP2 hooray for maxi K+.Cytoplasmic accumulation of long-chain coenzyme A esters activates KATP and inhibits Kir2.1 channels.Long chain CoA esters as competitive antagonists of phosphatidylinositol 4,5-bisphosphate activation in Kir channels.The Gq/G11-mediated signaling pathway is critical for autocrine potentiation of insulin secretion in miceThe antidepressant imipramine inhibits M current by activating a phosphatidylinositol 4,5-bisphosphate (PIP2)-dependent pathway in rat sympathetic neurones.Phosphatidylinositol 4,5-bisphosphate is acting as a signal molecule in alpha(1)-adrenergic pathway via the modulation of acetylcholine-activated K(+) channels in mouse atrial myocytes.Regulation of K(ATP) channels by P(2Y) purinoceptors coupled to PIP(2) metabolism in guinea pig ventricular cells.ATP-inhibition of M current in frog sympathetic neurons involves phospholipase C but not Ins P(3), Ca(2+), PKC, or Ras.Phosphatidylinositol 4,5-bisphosphate (PIP2) modulation of ATP and pH sensitivity in Kir channels. A tale of an active and a silent PIP2 site in the N terminus.Protein kinase C is necessary for recovery from the thyrotropin-releasing hormone-induced r-ERG current reduction in GH3 rat anterior pituitary cells.Zinc is both an intracellular and extracellular regulator of KATP channel function.Regulation of cardiac IKs potassium current by membrane phosphatidylinositol 4,5-bisphosphate.PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels.Impaired activation of ATP-sensitive K+ channels in endocardial myocytes from left ventricular hypertrophy.Characteristic interactions with phosphatidylinositol 4,5-bisphosphate determine regulation of kir channels by diverse modulators.Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K+ channels.Susceptibility of ATP-sensitive K+ channels to cell stress through mediation of phosphoinositides as examined by photoirradiation.
P2860
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P2860
Phospholipase C-linked receptors regulate the ATP-sensitive potassium channel by means of phosphatidylinositol 4,5-bisphosphate metabolism
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Phospholipase C-linked recepto ...... ol 4,5-bisphosphate metabolism
@en
type
label
Phospholipase C-linked recepto ...... ol 4,5-bisphosphate metabolism
@en
prefLabel
Phospholipase C-linked recepto ...... ol 4,5-bisphosphate metabolism
@en
P2093
P2860
P356
P1476
Phospholipase C-linked recepto ...... ol 4,5-bisphosphate metabolism
@en
P2093
P2860
P304
15292-15297
P356
10.1073/PNAS.96.26.15292
P407
P577
1999-12-01T00:00:00Z