Studies on calcium dependence reveal multiple modes of action for triptolide - Wikidata - awgldk - TriplyDB

Studies on calcium dependence reveal multiple modes of action for triptolide

Studies on calcium dependence reveal multiple modes of action for triptolide

http://www.wikidata.org/entity/Q36793607

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Triptolide (TPL) inhibits global transcription by inducing proteasome-dependent degradation of RNA polymerase II (Pol II).Triptolide inhibits proliferation and migration of colon cancer cells by inhibition of cell cycle regulators and cytokine receptors.Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease Targeting tumor proteasome with traditional Chinese medicine.Targeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer.Triptolide directly inhibits dCTP pyrophosphatase.Molecular understanding and modern application of traditional medicines: triumphs and trials.Triptolide-induced transcriptional arrest is associated with changes in nuclear substructure Natural products: chemical instruments to apprehend biological symphony.Triptolide induces anti-inflammatory cellular responses.Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms.Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation.Ontology-based systematic representation and analysis of traditional Chinese drugs against rheumatism.Targeting new cellular disease pathways in autosomal dominant polycystic kidney disease.

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Studies on calcium dependence reveal multiple modes of action for triptolide

http://www.wikidata.org/entity/Q36793607

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2005年の論文

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Studies on calcium dependence reveal multiple modes of action for triptolide

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Studies on calcium dependence reveal multiple modes of action for triptolide

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Studies on calcium dependence reveal multiple modes of action for triptolide

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Studies on calcium dependence reveal multiple modes of action for triptolide

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P356

J.CHEMBIOL.2005.09.009

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Chemistry and Biology

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Studies on calcium dependence reveal multiple modes of action for triptolide

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Craig M Crews

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Stephanie J Leuenroth

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P2860

Calcium oscillations increase the efficiency and specificity of gene expression

Regulation of cell death: the calcium-apoptosis link

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

The Ca2+(-)binding proteins parvalbumin and oncomodulin and their genes: new structural and functional findings.

Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. f.

Calcium and apoptosis: facts and hypotheses.

Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells.

Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway.

PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells.

NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillation

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1259-1268

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10.1016/J.CHEMBIOL.2005.09.009

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2486259

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