Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells.
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Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolideTriptolide in the treatment of psoriasis and other immune-mediated inflammatory diseasesTriptolide, an active compound identified in a traditional Chinese herb, induces apoptosis of rheumatoid synovial fibroblastsInhibition of nickel nanoparticles-induced toxicity by epigallocatechin-3-gallate in JB6 cells may be through down-regulation of the MAPK signaling pathwaysTriptolide induces growth inhibition and apoptosis of human laryngocarcinoma cells by enhancing p53 activities and suppressing E6-mediated p53 degradationIncreased cancer risk of augmentation cystoplasty: possible role for hyperosmolal microenvironment on DNA damage recognitionIdentification of triptolide, a natural diterpenoid compound, as an inhibitor of lung inflammation.Triptolide induces cell-cycle arrest and apoptosis of human multiple myeloma cells in vitro via altering expression of histone demethylase LSD1 and JMJD2B.Triptolide suppresses the in vitro and in vivo growth of lung cancer cells by targeting hyaluronan-CD44/RHAMM signaling.BH3-based fusion artificial peptide induces apoptosis and targets human colon cancer.Triptolide (TPL) inhibits global transcription by inducing proteasome-dependent degradation of RNA polymerase II (Pol II).Antagonist effect of triptolide on AKT activation by truncated retinoid X receptor-alphaTherapeutic impact of the ethyl acetate extract of Tripterygium wilfordii Hook F on nephritis in NZB/W F1 miceTriptolide, a constituent of immunosuppressive Chinese herbal medicine, is a potent suppressor of dendritic-cell maturation and traffickingHsp90 inhibitor BIIB021 enhances triptolide-induced apoptosis of human T-cell acute lymphoblastic leukemia cells in vitro mainly by disrupting p53-MDM2 balanceTriptolide induces s phase arrest and apoptosis in gallbladder cancer cells.Triptolide, histone acetyltransferase inhibitor, suppresses growth and chemosensitizes leukemic cells through inhibition of gene expression regulated by TNF-TNFR1-TRADD-TRAF2-NIK-TAK1-IKK pathway.Neuroprotective effects of DAHP and Triptolide in focal cerebral ischemia via apoptosis inhibition and PI3K/Akt/mTOR pathway activation.Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney diseaseIncreased epithelial and serum expression of macrophage migration inhibitory factor (MIF) in gastric cancer: potential role of MIF in gastric carcinogenesis.Suppression of the migration and invasion is mediated by triptolide in B16F10 mouse melanoma cells through the NF-kappaB-dependent pathway.Targeting tumor proteasome with traditional Chinese medicine.Targeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer.The triptolide derivative MRx102 inhibits Wnt pathway activation and has potent anti-tumor effects in lung cancer.Inhibition of epithelial ovarian cancer by Minnelide, a water-soluble pro-drug.Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5.Effective therapy for nephritis in (NZB x NZW)F1 mice with triptolide and tripdiolide, the principal active components of the Chinese herbal remedy Tripterygium wilfordii Hook F.Studies on calcium dependence reveal multiple modes of action for triptolideTriptolide-induced transcriptional arrest is associated with changes in nuclear substructureHerbal compound triptolide synergistically enhanced antitumor activity of amino-terminal fragment of urokinase.Apoptosis of human pancreatic cancer cells induced by Triptolide.Triptolide-mediated inhibition of interferon signaling enhances vesicular stomatitis virus-based oncolysis.Identification of retinoic acid-regulated nuclear matrix-associated protein as a novel regulator of gastric cancer.Triptolide induces anti-inflammatory cellular responses.Triptolide induces apoptosis in human leukemia cells through caspase-3-mediated ROCK1 activation and MLC phosphorylation.The ubiquitin-proteasome system in cancer, a major player in DNA repair. Part 2: transcriptional regulationNew Insights toward Colorectal Cancer Chemotherapy Using Natural Bioactive Compounds.Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms.Anticancer drugs from traditional toxic Chinese medicines.Triptolide with potential medicinal value for diseases of the central nervous system.
P2860
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P2860
Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Functional p53 is required for ...... ation in gastric cancer cells.
@en
type
label
Functional p53 is required for ...... ation in gastric cancer cells.
@en
prefLabel
Functional p53 is required for ...... ation in gastric cancer cells.
@en
P2093
P2860
P356
P1433
P1476
Functional p53 is required for ...... ation in gastric cancer cells.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204981
P407
P577
2001-11-01T00:00:00Z
P5875
P6179
1053383847