Regulation of protein O-glycosylation by the endoplasmic reticulum-localized molecular chaperone Cosmc. - Wikidata - awgldk - TriplyDB

Regulation of protein O-glycosylation by the endoplasmic reticulum-localized molecular chaperone Cosmc.

Regulation of protein O-glycosylation by the endoplasmic reticulum-localized molecular chaperone Cosmc.

http://www.wikidata.org/entity/Q36817899

about

ERK8 is a negative regulator of O-GalNAc glycosylation and cell migration Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice Co-translational function of Cosmc, core 1 synthase specific molecular chaperone, revealed by a cell-free translation system Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking Golgi targeting of Drosophila melanogaster beta4GalNAcTB requires a DHHC protein family-related protein as a pilot Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling)Entirely Carbohydrate-Based Vaccines: An Emerging Field for Specific and Selective Immune Responses The Origin and Activities of IgA1-Containing Immune Complexes in IgA Nephropathy The Role of Sialyl-Tn in Cancer Cosmc is an essential chaperone for correct protein O-glycosylation Platelet biogenesis and functions require correct protein O-glycosylation A testis-specific regulator of complex and hybrid N-glycan synthesis.Golgi UDP-GlcNAc:polypeptide O-α-N-Acetyl-d-glucosaminyltransferase 2 (TcOGNT2) regulates trypomastigote production and function in Trypanosoma cruzi.The endoplasmic reticulum chaperone Cosmc directly promotes in vitro folding of T-synthase.Biochemical characterization of functional domains of the chaperone Cosmc Immature truncated O-glycophenotype of cancer directly induces oncogenic features Identification of distinct glycoforms of IgA1 in plasma from patients with immunoglobulin A (IgA) nephropathy and healthy individuals A novel fluorescent assay for T-synthase activity.COSMC is overexpressed in proliferating infantile hemangioma and enhances endothelial cell growth via VEGFR2.The transmembrane domain of the molecular chaperone Cosmc directs its localization to the endoplasmic reticulum.Fc-glycosylation of IgG1 is modulated by B-cell stimuli.The immunomodulating roles of glycoproteins in epithelial ovarian cancer.A molecular chaperone mediates a two-protein enzyme complex and glycosylation of serine-rich streptococcal adhesins.Aberrant Cosmc genes result in Tn antigen expression in human colorectal carcinoma cell line HT-29.Promoters of Human Cosmc and T-synthase Genes Are Similar in Structure, Yet Different in Epigenetic Regulation Tight complex formation between Cosmc chaperone and its specific client non-native T-synthase leads to enzyme activity and client-driven dissociation.Epigenetic silencing of the chaperone Cosmc in human leukocytes expressing tn antigen Onco-Golgi: Is Fragmentation a Gate to Cancer Progression?Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology.Identification of ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) as a regulator of N-acetylglucosaminyltransferase GnT-IX (GnT-Vb).Systematic determination of the peptide acceptor preferences for the human UDP-Gal:glycoprotein-alpha-GalNAc beta 3 galactosyltransferase (T-synthase).Immunotherapy for cancer: synthetic carbohydrate-based vaccines.Tumor-associated glycans and their role in gynecological cancers: accelerating translational research by novel high-throughput approaches.O-glycan sialylation alters galectin-3 subcellular localization and decreases chemotherapy sensitivity in gastric cancer.Identification of a novel protein binding motif within the T-synthase for the molecular chaperone Cosmc.The Tn antigen-structural simplicity and biological complexity.Golgi glycosylation and human inherited diseases.Tn and sialyl-Tn antigens, aberrant O-glycomics as human disease markers.The Cosmc connection to the Tn antigen in cancer.Simple sugars to complex disease--mucin-type O-glycans in cancer.

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P2860

Regulation of protein O-glycosylation by the endoplasmic reticulum-localized molecular chaperone Cosmc.

http://www.wikidata.org/entity/Q36817899

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Regulation of protein O-glycos ...... zed molecular chaperone Cosmc.

@ast

Regulation of protein O-glycos ...... zed molecular chaperone Cosmc.

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type

label

Regulation of protein O-glycos ...... zed molecular chaperone Cosmc.

@ast

Regulation of protein O-glycos ...... zed molecular chaperone Cosmc.

@en

prefLabel

Regulation of protein O-glycos ...... zed molecular chaperone Cosmc.

@ast

Regulation of protein O-glycos ...... zed molecular chaperone Cosmc.

@en

P1433

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P1433

Journal of Cell Biology

P1476

Regulation of protein O-glycos ...... zed molecular chaperone Cosmc.

@en

P2093

Caleb J Stowell

http://www.w3.org/2001/XMLSchema#string

Rajindra P Aryal

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Richard D Cummings

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Tongzhong Ju

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P2860

Cloning and expression of human core 1 beta1,3-galactosyltransferase

A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase

N-glycan processing in ER quality control

Protein folding and quality control in the endoplasmic reticulum

ER chaperones in mammalian development and human diseases

Defective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans.

Quality control in the endoplasmic reticulum

Molecular cloning and characterization of a novel UDP-Gal:GalNAc(alpha) peptide beta 1,3-galactosyltransferase (C1Gal-T2), an enzyme synthesizing a core 1 structure of O-glycan.

Identification of core 1 O-glycan T-synthase from Caenorhabditis elegans.

P304

531-542

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scholarly article

P356

10.1083/JCB.200711151

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3

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182

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23163673

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18695044

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P921

molecular chaperones

endoplasmic reticulum

P932

2500138

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