Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse
about
Disruption of maternal DNA repair increases sperm-derived chromosomal aberrationsTranscription factor zinc finger and BTB domain 1 is essential for lymphocyte developmentColorectal cancer models for novel drug discoveryGenomic structure of mouse and human genes for DNA-PKcs interacting protein (KIP)Carboxyl-terminal region conserved among phosphoinositide-kinase-related kinases is indispensable for mTOR function in vivo and in vitroKu70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombinationMouse models of Fanconi anemiaLoss of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in gastric cancersRole of DNA-dependent protein kinase catalytic subunit in cancer development and treatmentTherapeutic efficacy of human hepatocyte transplantation in a SCID/uPA mouse model with inducible liver diseaseFunctional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombinationLate activation of stress kinases (SAPK/JNK) by genotoxins requires the DNA repair proteins DNA-PKcs and CSBDefective DNA repair and increased genomic instability in Artemis-deficient murine cellsInteraction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acidsAnimal models for HIV/AIDS researchMolecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20Computational analysis of retrovirus-induced scid cell death.Human allograft rejection in humanized mice: a historical perspectiveAnalysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation.A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages.Nijmegen breakage syndrome: consequences of defective DNA double strand break repair.Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development.SCID dogs: similar transplant potential but distinct intra-uterine growth defects and premature replicative senescence compared with SCID mice.Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang.Failure of hairpin-ended and nicked DNA To activate DNA-dependent protein kinase: implications for V(D)J recombinationInhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs)Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and developmentHuman TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition.Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoiningThe p53 response to DNA damage in vivo is independent of DNA-dependent protein kinaseIrradiation promotes V(D)J joining and RAG-dependent neoplastic transformation in SCID T-cell precursors.The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.Disruption of pre-TCR expression accelerates lymphomagenesis in E2A-deficient miceCyclin D3 promotes pancreatic β-cell fitness and viability in a cell cycle-independent manner and is targeted in autoimmune diabetes.Enzymatic processing of DNA containing tandem dihydrouracil by endonucleases III and VIII.A single amino acid substitution in DNA-PKcs explains the novel phenotype of the CHO mutant, XR-C2.Drosophila target of rapamycin kinase functions as a multimer.Primary immunodeficiency diseases: natural mutant models for the study of the immune system.XR-C1, a new CHO cell mutant which is defective in DNA-PKcs, is impaired in both V(D)J coding and signal joint formation.Double strand break repair.
P2860
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P2860
Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Identification of a nonsense m ...... ytic subunit in the scid mouse
@en
type
label
Identification of a nonsense m ...... ytic subunit in the scid mouse
@en
prefLabel
Identification of a nonsense m ...... ytic subunit in the scid mouse
@en
P2093
P2860
P356
P1476
Identification of a nonsense m ...... ytic subunit in the scid mouse
@en
P2093
P2860
P304
10285-10290
P356
10.1073/PNAS.93.19.10285
P407
P577
1996-09-01T00:00:00Z