about
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesRedox mechanisms in hepatic chronic wound healing and fibrogenesisMicroglial cell dysregulation in brain aging and neurodegenerationRole of environmental contaminants in the etiology of Alzheimer's disease: a reviewGlycated albumin: an overview of the In Vitro models of an In Vivo potential disease markerNeuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glassOxidized cholesterol as the driving force behind the development of Alzheimer's diseaseQuantification of copper binding to amyloid precursor protein domain 2 and its Caenorhabditis elegans ortholog. Implications for biological functionEffects of age, dietary, and behavioral enrichment on brain mitochondria in a canine model of human agingThe ubiquitin-proteasome system in Alzheimer's diseaseDeficiency of the copper chaperone for superoxide dismutase increases amyloid-β productionIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesAge-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cellsAmyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive declineA new chiral pyrrolyl α-nitronyl nitroxide radical attenuates β-amyloid deposition and rescues memory deficits in a mouse model of Alzheimer diseaseOmega-3 fatty acids and cognitive function in women.Redox control of prion and disease pathogenesis.Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies.Discovery of 5-(4-hydroxyphenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide as a neuroprotectant for Alzheimer's disease by hybridization of curcumin and melatoninThe amyloid-beta peptide of Alzheimer's disease binds Cu(I) in a linear bis-his coordination environment: insight into a possible neuroprotective mechanism for the amyloid-beta peptideIndoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease.Oligomeric forms of insulin amyloid aggregation disrupt outgrowth and complexity of neuron-like PC12 cells.Recent Development of Bifunctional Small Molecules to Study Metal-Amyloid-β Species in Alzheimer's DiseaseDesign of small molecules that target metal-A{beta} species and regulate metal-induced A{beta} aggregation and neurotoxicity.Synthetic Flavonoids, Aminoisoflavones: Interaction and Reactivity with Metal-Free and Metal-Associated Amyloid-β SpeciesNeuroprotective strategies involving ROS in Alzheimer disease.Role of metal dyshomeostasis in Alzheimer's disease.Degeneration modulates retinal response to transient exogenous oxidative injury.Oxidative stress in oral diseases.Amyloid β: linking synaptic plasticity failure to memory disruption in Alzheimer's diseaseNeuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathologyInvolvement of molecular chaperones and the transcription factor Nrf2 in neuroprotection mediated by para-substituted-4,5-diaryl-3-thiomethyl-1,2,4-triazinesDiscovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's diseaseAssociation of the C47T Polymorphism in SOD2 with Amnestic Mild Cognitive Impairment and Alzheimer's Disease in Carriers of the APOEε4 AlleleOpportunities in multidimensional trace metal imaging: taking copper-associated disease research to the next levelReactivity of diphenylpropynone derivatives toward metal-associated amyloid-β species.DHA Hydroperoxides as a Potential Inducer of Neuronal Cell Death: a Mitochondrial Dysfunction-Mediated Pathway.Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model.Mechanistic Insight of Bivalent Compound 21MO as Potential Neuroprotectant for Alzheimer's DiseaseIn inclusion-body myositis muscle fibers Parkinson-associated DJ-1 is increased and oxidized.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Causes of oxidative stress in Alzheimer disease.
@en
type
label
Causes of oxidative stress in Alzheimer disease.
@en
prefLabel
Causes of oxidative stress in Alzheimer disease.
@en
P2093
P1476
Causes of oxidative stress in Alzheimer disease
@en
P2093
P2888
P304
P356
10.1007/S00018-007-7218-4
P577
2007-09-01T00:00:00Z